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The Assessment of Periodontal Status and Treatment Needs of the Adult Population Aged 34-44 Residing in Lublin Province and Visiting the Dentist Regularly

100%
Stodókiewicz M., Krawczyk J., Szkutnik J., Berger M.
Polish Journal of Public Health
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2015
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vol. 124
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issue 2
86-88
EN
Introduction. Periodontitis is a group of inflammatory disorders affecting periodontal tissues. This condition manifests by a progressive destruction of the alveolar bone, subsequently leading to tooth loss. World Health Organization introduced Community Periodontal Index of Treatment Needs in order to gain data regarding periodontal health and treatment needs of people with periodontitis Aim. To evaluate the periodontal status of citizens living in the city of Lublin and its surrounding, using Community Periodontal Index of Treatment Needs (CPITN). Material and methods. Community Periodontal Index of Treatment Needs was used to assess the periodontal status among 180 patients aged 35-44 residing in Lublin and the area around it. Results. Periodontal diseases have been observed in over 90% of the examined population. Treatment need index TN1 has referred to 26.11% of the patients, TN2 – 61.67% and TN3 – 2.22% respectively. Conclusions. Patients who visit the dentist regularly have a better periodontal status as compared to groups randomly selected.
2
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Gingival Crevicular Fluid – Composition and Clinical Importance in Gingivitis and Periodontitis

100%
Rahnama M., Czupkałło Ł., Kozicka-Czupkałło M., Łobacz M.
Polish Journal of Public Health
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2015
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vol. 124
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issue 2
96-98
EN
Among many substances used in clinical diagnosis, such as peripheral blood, gum homogenate, saliva and gingival pocket fluid, it is the latter that seems to bean extremely valuable diagnostic and research material. Identification of mediators in gingival crevicular fluid, both in the healthy gingival fissure, as well as in pathological periodontal pockets can be a valuable supplement to the initial diagnosis and describe the mechanism of gumorperiodontal diseases. Changes in the concentration of individual components in the gingival crevicular fluid may be used to assess the severity of periodontal disease. There are numerous methods for collecting fluid from the sulcus described: Micro-capillary drainage, micropipette drainage, rinsing pocket or drainage with the use of methylcellulose strips and then reading with Periotron. Gingival fluid is composed mainly of blood electrolytes and organic molecules, i.e. albumins, globulins, lipoproteins or fibrinogen and cellular components as well as peptides, bacteria and enzymes. Therefore gingival crevicular fluid (GCF) is treated as a window for noninvasive analysis of periodontitis, taking into account indicators and markers of connective tissue and bone destruction.
3
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Protective effect of 6-shogaol against endotoxin-induced periodontitis in rats

75%
Qi H., Han B.
Acta Poloniae Pharmaceutica - Drug Research
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2018
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vol. 75
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issue 6
1391-1398
EN
Periodontal diseases are the most prevalent bacterial ailments, affecting 10–15% of the global population, and eventually leading to tooth loss if left untreated. Shogaols obtained from ginger (Zingiber officinale) exhibit significant anti-inflammatory activity. However, the antibacterial potential of shogaols against periodontitis remains unexplored. Therefore, we investigated the effects of 6-shogaol (6-SH) on various factors responsible for periodontitis such as inflammation. Escherichia coli endotoxin was used to induce experimental periodontitis, and the effects of 6-SH on hydrogen peroxide, superoxide anion, myeloperoxidase activity, and lipid peroxides were estimated together with cathepsin B, cathepsin D, β-glucuronidase, acid phosphatase, and C-reactive protein activity in serum. In addition, the levels of ascorbic acid, α-tocopherol, ceruloplasmin, reduced glutathione, superoxide dismutase, catalase, glutathione peroxidase, and glutathione S-transferase were estimated in serum after 6-SH treatment. Reactive oxygen species and lipid peroxide levels were significantly reduced in the 6-SH-treated group. Moreover, lysosomal enzyme (cathepsin B, cathepsin D, β-glucuronidase and acid phosphatase) and acute-phase protein (C-reactive protein and fibrinogen) levels significantly declined after administration of 6-SH. Meanwhile, non-enzymatic antioxidant systems (e.g., ascorbic acid, α-tocopherol, ceruloplasmin, and reduced glutathione) and antioxidant enzymes (e.g., catalase, superoxide dismutase, glutathione peroxidase, and glutathione S-transferase) were significantly increased in the 6-SH-treated group. These results suggest a protective effect of 6-SH against experimental periodontitis via the regulation of key disease markers.
4
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Остеостимулююча дія полівалентного орального гелю на стан кісткової тканини нижньої щелепи щурів з преднізолоновим пародонтитом

63%
Levitsky A. P., Borysenko A. V., Stolyar V. G.
Journal of Health Sciences
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2014
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vol. 4
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issue 6
21-30
EN
Osteostimulatory Effect of Polyvalent Oral Gel on the Bone Tissue of the Rats’ Lower Jaw with Prednisolon Periodontitis A. P. Levitsky, A. V. Borysenko, V. G. Stolyar Objective. To determine osteostimulating effect of polyvalent oral gel on the bone when modeling periodontal prednisolon periodontitis. Materials and Methods. We used polyvalent oral gel containing osteovit (calcium citrate, soy isoflavones, zinc sulfate and vitamin D3), propolis tincture, metrogil-dent, chlorhexidine and silica, which was applied to the oral mucosa in applications during two weeks to rats which recieved prednisolon-containing feed. Altogether, 32 rats. As a comparison drug we used mefenat. Results. The reduction of acid phosphatase activity and increase of the mineralizing index, increase and the ratio of calcium content calcium/protein in the bone tissue under the influence of a polyvalent gel was achieved. Conclusion. Proposed gel has osteostimulating effect.
PL
ОСТЕОСТИМУЛИРУЮЩЕЕ ДЕЙСТВИЕ ПОЛИВАЛЕНТНОГО ОРАЛЬНОГО ГЕЛЯ НА СОСТОЯНИЕ КОСТНОЙ ТКАНИ НИЖНЕЙ ЧЕЛЮСТИ КРЫС С ПРЕДНИЗОЛОНОВЫМ ПАРОДОНТИТОМ А. П. Левицкий, А. В. Борисенко, В. Г. Столяр Поливалентный оральный гель (ПОГ), состоящий из остеовита, настойки прополиса, метрогил-дента, хлоргексидина и диоксида кремния, оказывает остеостимулирующее действие на костную ткань пародонта крыс с преднизолоновым пародонтитом: снижает активность кислой фосфатазы, увеличивает соотношение щелочная фосфатаза/кислая фосфатаза и степень минерализации, снижает степень атрофии альвеолярного отростка
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