In everyday medical practice, finding the exact cause of conjunctivitis can be difficult without thorough laboratory testing. Therefore, the paper presents cases of treating ocular surface disorders of unknown etiology with the help of combination preparations in the form of a suspension, which allows a wide range of therapeutic effects including bacteria, chlamydia and allergic inflammation and provides a more stable and longer-lasting drug concentration level compared to drugs in the form of aqueous solutions.
Ocular surface disorders, including dry eye disease, affect 5–50% of the population, with prevalence increasing with age, especially among women. Symptoms such as dryness, burning, and eye fatigue significantly reduce quality of life. The tear film consists of aqueous-mucin and lipid fractions, providing protection and hydration for the eye. Meibomian gland dysfunction, which disrupts the lipid layer, accounts for most cases of dry eye disease by causing excessive tear evaporation. A modern approach to ocular surface disorder therapy, combining pharmacotherapy, neuromodulation, and advanced technologies, may relieve daily chronic eye pain.
Ophthalmic surgeries, including cataract surgery, lead to higher occurrence of eye surface disease. Tear film abnormalities are present in more than 60% of cataract patients. Patients with increased risk of perioperative dry eye syndrome should be treated before the surgery. Artificial tears are the first line treatment. In case they are insufficient, immunomodulants are used. Eyelid margin hygiene also exerts positive effect in patients with Meibomian gland dysfunction. Out of artificial tears ingredients, hyaluronic acid and Ginkgo biloba extract show positive effect.
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