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Simple synthesis of 3-acyl-5-alkyl(aryl)isoxazoles from terminal alkynes and nitrates of alkaline metals or ammonium

100%
Rogachev V., Filimonov V., Kulmanakova J., Yusubov M., Bender W.
Open Chemistry
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2005
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vol. 3
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issue 3
370-376
EN
A simple and general synthesis of 3-acyl-5-alkyl(aryl)isoxazoles by reaction of terminal alkynes with nitrates in acetic acid in the presence of SO3 or alkaline salts is described.
2
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Influence of Beetroot Supplementation on Oxygen Muscle Saturation of Semi-Professional Soccer Players Following a Repeated Sprint Test

100%
Michailidis Y.
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vol. 42
55-63
EN
Dietary nitrates have hemodynamic and metabolic effects on the body. This study aimed to investigate nitrate intake's effect on quadricep muscle oxygen saturation (StO2) of semi-professional soccer players during a repeated speed test (RSA). In a randomized, crossover design, 10 semi-professional soccer men players (21.3 ± 0.9yrs) performed two conditions: In one they consumed a nitrate-rich concentrated beetroot juice (250 mL/150 mg of NO3−) and in the other a placebo, 2h before a repeated sprint test. StO2 of the right vastus lateralis muscle was measured by near-infrared spectroscopy. A paired samples t-test was used to compute any differences in the subjects’ performance on the StO2 and on RSA test. The level of significance was set at p < 0.05. The supplementation of nitrates limited the decrease in muscle oxygenation during the six sprints of RSA test (p < 0.001) and also, there seemed to be a tendency for limited the decrement of performance on RSA test (t = -1.586, p = 0.157, η2 = 0.218). In conclusion, acute nitrate supplementation reduces the decrement of muscle oxygenation during exercise with repeated sprints and leads to a tendency of fatigue resistance during repeated sprints under controlled situations. Nitrate supplementation may have an ergogenic effect during exercise with repeated sprints via the higher muscle oxygenation.
3
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Beetroot Juice - Legal Doping for Athletes?

88%
Kurowska K., Antosik K., Kobylińska M., Decyk A.
Central European Journal of Sport Sciences and Medicine
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2021
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vol. 35
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issue 3
57-70
EN
Nitric oxide (NO) is a physiologically important signaling molecule that promotes the expansion of blood vessels and thus facilitates the transport of oxygen (O2) and energy substrates to the muscles. Research shows that nitric oxide (NO) also improves the effectiveness of mitochondrial respiration, which is manifested by reduced oxygen consumption during exercise. Until recently, it was thought that nitric oxide (NO) could only be formed as a result of the endogenous pathway of oxidative transformations L-arginine. Recent research results indicate, however, that an alternative to the endogenous pathway of nitric oxide (NO) formation may be the exogenous supply of inorganic nitrates (NO3-) with food. The aim of the study was to review the current literature on the properties of beetroot juice as an important source of nitrates (NO3-) and its effectiveness in improving the exercise capacity of physically active people. A systematic review of the research, published from 2005 to January 31, 2021, was made on the basis of searching bibliographic databases such as: PubMed, Elsevier and Web of Science. The following keywords were used: “beetroot”, “beetroot juice”, “nitrates”, “nitrites”, “nitric oxide”, “supplementation”, “ergogenic substances”, “sports nutrition”. Although there are conflicting data, it appears that beetroot juice supply may be a cheap, natural, and promising nutritional strategy for improving sports performance in both endurance and intermittent high intensity (start-stop) exercise. More detailed studies are analyzing the effect of dietary nitrate (NO3-) supply in anaerobic exercise - especially in high-volume resistance training - are needed. It is also emphasized that further research is needed to elucidate the effects of specific factors on the variability of ergogenic effects after beetroot juice consumption, which may be of the greatest importance in terms of the effectiveness of this nutritional intervention.
4
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Monitoring of basic physicochemical parameters in the flow and their possible influence on the quality of the small water source

75%
Oppeltová P., Boráková J., Oppeltová P., Boráková J.
Journal of Water and Land Development
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2020
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issue 44
5
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Promising method of ion exchange separation of anions before reverse osmosis

75%
Trus I., Gomelya M., Vorobyova V., Skіba M., Trus I., Gomelya M., Vorobyova V., Skіba M.
Archives of Environmental Protection
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2021
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vol. 47
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issue 4
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