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Background: The middle cerebral artery (MCA) supplies a major part of the brain and is of considerable clinical importance as a common location of intracranial aneurysms. The aim of the present study was to analyze the bilateral MCAs in patients with unilateral aneurysms. Material and methods: Images of computed tomography angiography of 45 patients were analyzed. The morphometric parameters of MCA were measured. The measured parameters of the normal MCAs were compared with MCAs containing aneurysms located in the main trunk division. Results: No significant differences in the length of trunk and angles between the middle and anterior cerebral arteries were found between the non-affected and aneurysmatic MCAs. Concerning arteries with aneurysms, more branches originating from the main trunk division were found more frequently. The coexistence of the more frequent trifurcation of the MCA and an aneurysm constitutes evidence of greater anatomical variability of this arterial area in cases with a concomitant vascular malformation. Conclusions: This finding is consistent with literature data, showing the relationship between aneurysms and arterial variability and the fact that aneurysms are most often located at arterial divisions.
EN
Insulin-like growth factor type 1 (IGF-1) belongs to the peptide hormones which regulate cell proliferation and differentiation as well as angiogenesis. The aim of the present study was the quantitative evaluation of immuohistochemical (IH) expression of IGF-1 and its two receptors (IGF-1Rα and IGF-1Rβ) parallel to changes of capillary lumen/whole capillary area (L/W) ratio during the perinatal period. Tissue samples from lungs from 19-, and 21-day fetuses as well as 1-, 3-, 5-day old newborns were processed for frozen sections that were used for IH staining and then used for quantitative analysis of antigens expression. In parallel, tissue samples were processed for transmission electron microscopy and used for capillaries morphometry. Our results were statistically evaluated. We found that the expression of IGF-1 in the peripheral part of the developing lung has a peak at the moment of birth when changes of vascular structure were reflected by L/W ratio. This is followed by the peak expression of the IGF-1Rα, but not of the IGF-1Rβ.
EN
Is it possible that in Poland, instead of Morasko and still unconfirmed structures Porzadzie, Jaszczulty and Ochudno, may exist some other impact craters? To answer this question, investigations were performed, which were based on the digital elevation models. There are plenty of cavities, having different origin (e.g. a result of past glaciations, human activities or the Second World War), where some criteria may be applied, which could help to distinguish one from another. The main assumption was that during oblique impact (low angle in relation to the surface) there may develop special type of craters having cardioid (heart-shaped) ejecta pattern (as well as shape of cavity), with axis of symmetry parallel to the initial trajectory. Such structures were observed many times during experiments as well as can be easily found on other celestial bodies. Having preserved rims, even if they are much shallower than typical craters (because of secondary changes), such cavities are perfect candidates to be suspected of the impact origin. As a result of research between 2015 and 2017 there were discovered 3 locations (instead of Ochudno) with heart-shaped structures, which may represent combined effect of ejection angles, velocities and directions, known from experiments and confirmed craters. In all cases there are noticeable rims. The largest “spoon-like” structure, discovered near the Rowista village, is almost perfect copy of a very unusual elongated crater located north of the Acheron Fossae on Mars.
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