Search results

Search:
in the keywords: hematite nanoparticles

Sort By:

Limit search:

Mobility of interacting inorganic nanoparticles

100%

Dziedzic-Kocurek K., Fornal P., Stanek J.

Nukleonika

2015

vol. 60

issue 1

19-22

The mobility of the 110 nm-Fe2O3 particles in a viscous sucrose solution depends on the concentration of the nanoparticles. When the average particle–particle nearest neighbor distance is less than 250 nm, the particle interaction slows down their mobility. When is more than 170 nm, the small mobility of nanoparticles does not depend on their concentration. The critical distance is approximately equal to 2Rh = 260 nm, where Rh is the hydrodynamic radius, determined by the dynamic light scattering (DLS) method.

Depletion of intracellular glutathione and increased lipid peroxidation mediate cytotoxicity of hematite nanoparticles in MRC-5 cells

100%

Radu M., Munteanu M. C., Petrache S., Serban A. I., Dinu D., Hermenean A., Sima C., Dinischiotu A.

Acta Biochimica Polonica

2010

vol. 57

issue 3

355-360

Particles generated from numerous anthropogenic and/or natural sources, such as crystalline α-Fe2O3 nanoparticles, have the potential to damage lung cells. In our study we investigated the effects of these nanoparticles (12.5 µg/ml) on lipid peroxidation and the antioxidative system in MRC-5 lung fibroblast cells following exposure for 24, 48 or 72h. Exposure to α-Fe2O3 nanoparticles increased lipid peroxidation by 81%, 189% and 110% after 24, 48 and 72h, respectively. Conversely, the reduced glutathione concentration decreased by 23.2% and 51.4% after 48 and 72h of treatment, respectively. In addition, an augmentation of the activities of superoxide dismutase, catalase, glutathione peroxidase, glutathione transferase and glutathione reductase within the interval between 48-72h was noticed. Taking into account that the reduced glutathione level decreased and the malondialdehyde level, a lipid peroxidation product, remained highly increased up to 72h of exposure, it would appear that the MRC-5 antioxidant defense mechanisms did not efficiently counteract the oxidative stress induced by exposure to hematite nanoparticles.

Refine search results

1 Acta Biochimica Polonica

1 Nukleonika

1 2015

1 2010

1 Dinischiotu A.

1 Dinu D.

1 Dziedzic-Kocurek K.

1 Fornal P.

1 Hermenean A.

1 Munteanu M. C.

1 Petrache S.

1 Radu M.

1 Serban A. I.

1 Sima C.

1 Stanek J.

Search results

Mobility of interacting inorganic nanoparticles

Depletion of intracellular glutathione and increased lipid peroxidation mediate cytotoxicity of hematite nanoparticles in MRC-5 cells