Search results

1

Analysis of heart rate variability during head-up tilt-test in patients with vasovagal syncope

100%

Budrejko S., Kempa M., Chmielecka M., Kozłowski D., Raczak G.

|

issue 1

26-38

EN

Introduction Syncope is defined as transient loss of consciousness, due to decrease in brain perfusion. The most frequent mechanism is vasovagal syncope. In many patients, the cause of syncope remains unspecified, despite an extensive diagnostic work-up. Tilt-test (TT) is an acknowledged diagnostic tool for syncope. Currently, the so-called Italian protocol of TT is most widely used. Vasovagal syncope is caused by impaired circulatory regulation in response to orthostatic stress. One of the available tools to examine the influence of the nervous system on the circulation is the analysis of heart rate variability (HRV). Despite numerous publications concerning HRV parameters and autonomic regulation in patients with syncope, direct comparisons and metaanalysis of the results is impossible, due to variability of TT protocols and study group specifications. Aim of the study As there is no uniform model of HRV during TT, we aimed to analyze HRV parameters during TT (performed according to the Italian protocol) in patients with vasovagal syncope, in order to determine the possible application of HRV measurements in clinical practice in that group of patients. Detailed objectives were: (1) analysis and comparison of HRV in patients with and without the history of syncope; (2) analysis of HRV changes in consecutive stages of TT; (3) identification of possible HRV differences between patients with positive and negative TT results. Materials and methods Patients between 18 and 50 years of age were qualified for the study, if they had a history of at least 2 incidents of syncope or presyncope within the preceeding 6 months, and if signs and symptoms indicated the vasovagal mechanism. The study group included 150 patients: 100 consecutive patients with a postive TT result (POS), and 50 consecutive patients with a negative TT result (NEG). The control group (CG) comprised 50 volunteers with no history of syncope nor presyncope, matched according to age and sex to the study group. In all patients a TT was performed according to the Italian protocol, with paced breathing at a rate of 15/min. Time-domain (meanRR, SDNN, RMSSD, pNN50) and frequency-domain (abs_LF, abs_HF, rel_LF, rel_HF, norm_LF, norm_HF, LF/HF) HRV parameters were analyzed and compared at different stages of TT in the study groups as specified above. Results 100 patients at the age of 18-44 years were included in the POS group, 50 patients at the age of 18-39 years in the NEG group, and 50 volunteers at the age of 20-39 in the CG. Volunteers in the control group developed unexpectedly high percentage of positive TT (14 patients). For consistency of analysis, the CG was thus subdivided according to the result of the TT into CG_POS (positive result of TT) – 14 patients, and CG_NEG (negative result of TT) – 36 patients. Based on HRV analaysis, no significant differences in HRV values were noted between patients with a history of syncope and positive or negative result of TT. Upright tilt resulted in HRV changes of the same direction and value in syncopal patients in the POS and NEG goup, as well as in patients in the CG_NEG group. Conclusion HRV values and changes of those values at subsequent stages of TT were not different between syncopal patients with postive or negative TT result, or negative TT control group. The Italian protocol of TT may be associated with a surprisingly high percentage of false positive results.

2

Cardiopulmonary resonance at 0.1 Hz demonstrated by averaged Lomb-Scargle periodogram

100%

Piskorski J., Guzik P., Krauze T., Żurek S.

|

EN

We demonstrate the resonant-like behaviour of the cardiopulmonary system in healthy people occurring at the natural low frequency oscillations of 0.1 Hz, which are often visible in the continuous pressure waveform. These oscillations represent the spontaneous oscillatory activity of the vasomotor centre and are sometimes called the Mayer waves. These 10-second rhythms probably couple with forced breathing at the same frequency and cause the observed cardiopulmonary resonance phenomenon. We develop a new method to study this phenomenon, namely the averaged Lomb-Scargle periodogram method, which is shown to be very effective in enhancing common frequencies in a group of different time series and suppressing those which vary between datasets. Using this method we show that in cardiopulmonary resonance the cardiopulmonary system behaves in a very similar way to a simple mechanical or electrical oscillator, i.e. becomes highly regular and its averaged spectrum exhibits a clear dominant peak and harmonics. If the forcing frequency is higher than 0.1 Hz, the total power and the share of power in the dominant peak and harmonics are lower and the prominence of the dominant peak and its harmonics greatly diminishes. It is shown that the power contributions from different forcing frequencies follow the resonance curve.

3

Characteristics of autonomic nervous system function in individuals after spinal cord injury

100%

Piesiewicz K., Żurowska A., Jethon Z., Bolach E.

Physiotherapy

|

2009

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vol. 17

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issue 2

12-16

PL

Cel i założenia: celem badań było porównanie równowagi pomiędzy składową sympatyczną i parasympatyczną u osób po uszkodzeniu rdzenia kręgowego. Materiał badawczy: przebadano 10 nietrenujących mężczyzn po urazie rdzenia kręgowego w wieku 17-34 lat. Metoda badawcza: pomiary zmienności rytmu zatokowego serca (HRV) oraz częstości skurczów serca (HR) zostały wykonane za pomocą sport-testera S 810i firmy Polar. Zarejestrowane pliki HR posłużyły do analizy zmienności rytmu zatokowego serca w programie HRV Analysis. Wnioski: przewaga mocy w zakresie niskich częstotliwości może świadczyć o dominacji części sympatycznej autonomicznego układu nerwowego. Niższa wartość mocy całkowitej u osób niepełnosprawnych może wskazywać dezorganizację w funkcjonowaniu autonomicznego układu nerwowego.

EN

Purpose of the study: the aim of the study was to compare sympathetic and parasympathetic balance in patients after spinal cord injury. Subjects: ten sedentary men after spinal cord injury at the age of 17-34 were examined. Method: the variability of the sinus rhythm (HRV) as well as the heart rate were measured by means of the Polar sport-tester S 810i. The collected data was used to analyse the sinus rhythm's variability in HRV Analysis program. Conclusions: the prevalence of low frequencies may signify/indicate dominance of sympathetic element of the autonomic nervous system. Lower values of the total force may show dysfunctioning of the autonomic nervous system after spinal cord injury.

4

Analysis of heart rate variability during head-up tilt-test in patients with vasovagal syncope

100%

Budrejko S., Kempa M., Chmielecka M., Kozłowski D., Raczak G.

European Journal of Translational and Clinical Medicine

|

2018

|

vol. 1

|

issue 1

26-38

EN

Introduction: Syncope is defined as transient loss of consciousness, due to decrease in brain perfusion. The most frequent mechanism is vasovagal syncope. In many patients, the cause of syncope remains unspecified, despite an extensive diagnostic work-up. Tilt-test (TT) is an acknowledged diagnostic tool for syncope. Currently, the so-called Italian protocol of TT is most widely used. Vasovagal syncope is caused by impaired circulatory regulation in response to orthostatic stress. One of the available tools to examine the influence of the nervous system on the circulation is the analysis of heart rate variability (HRV). Despite numerous publications concerning HRV parameters and autonomic regulation in patients with syncope, direct comparisons and metaanalysis of the results is impossible, due to variability of TT protocols and study group specifications. Aim of the study: As there is no uniform model of HRV during TT, we aimed to analyze HRV parameters during TT (performed according to the Italian protocol) in patients with vasovagal syncope, in order to determine the possible application of HRV measurements in clinical practice in that group of patients. Detailed objectives were: (1) analysis and comparison of HRV in patients with and without the history of syncope; (2) analysis of HRV changes in consecutive stages of TT; (3) identification of possible HRV differences between patients with positive and negative TT results. Materials and methods: Patients between 18 and 50 years of age were qualified for the study, if they had a history of at least 2 incidents of syncope or presyncope within the preceeding 6 months, and if signs and symptoms indicated the vasovagal mechanism. The study group included 150 patients: 100 consecutive patients with a postive TT result (POS), and 50 consecutive patients with a negative TT result (NEG). The control group (CG) comprised 50 volunteers with no history of syncope nor presyncope, matched according to age and sex to the study group. In all patients a TT was performed according to the Italian protocol, with paced breathing at a rate of 15/min. Time-domain (meanRR, SDNN, RMSSD, pNN50) and frequency-domain (abs_LF, abs_HF, rel_LF, rel_HF, norm_LF, norm_HF, LF/HF) HRV parameters were analyzed and compared at different stages of TT in the study groups as specified above. Results: 100 patients at the age of 18-44 years were included in the POS group, 50 patients at the age of 18-39 years in the NEG group, and 50 volunteers at the age of 20-39 in the CG. Volunteers in the control group developed unexpectedly high percentage of positive TT (14 patients). For consistency of analysis, the CG was thus subdivided according to the result of the TT into CG_POS (positive result of TT) – 14 patients, and CG_NEG (negative result of TT) – 36 patients. Based on HRV analaysis, no significant differences in HRV values were noted between patients with a history of syncope and positive or negative result of TT. Upright tilt resulted in HRV changes of the same direction and value in syncopal patients in the POS and NEG goup, as well as in patients in the CG_NEG group. Conclusion: HRV values and changes of those values at subsequent stages of TT were not different between syncopal patients with postive or negative TT result, or negative TT control group. The Italian protocol of TT may be associated with a surprisingly high percentage of false positive results.

5

The influence of montelukast on the autonomic nervous system activity in rats with cyclophosphamide-induced hemorrhagic cystitis

100%

Dobrek L., Skowron B., Baranowska A., Thor P. J.

Current Issues in Pharmacy and Medical Sciences

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2015

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vol. 28

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issue 3

170-175

EN

The complex pathogenesis of cyclophosphamide-induced hemorrhagic cystitis involves arachidonic acid-derived inflammatory mediators, among them leukotrienes. Montelukast, a leukotriene receptor antagonist, is reported to exert an alleviatory effect in the course of cystitis associated with overactive bladder symptoms. The aim of this study was to verify whether the effect of montelukast is also associated with its influence on autonomic activity. The experiment included 20 rats with cyclophosphamide-induced hemorrhagic cystitis (75 mg/kg, four doses every second day), among them, 10 treated with oral montelukast (10 mg/kg for 8 days) and 10 controls. Time and frequency domain analyses of heart rate variability (HRV) were conducted in all the rats as an indirect measure of their autonomic activity. The montelukast-treated animals showed an increase in root mean square of successive differences (rMSSD), as well as an increase in HRV spectrum total power (TP) and power of very low (VLF) spectral component. This suggests that due to its anti-inflammatory and its anti-leukotriene effect, montelukast improves overall autonomic activity, with no preferential influence on either the sympathetic or parasympathetic part. Furthermore, the increase in VLF corresponds to attenuation of inflammatory response. In conclusion, this study showed that aside from its antagonistic effect on leukotriene receptors, montelukast can also modulate autonomic activity.

6

Prenatal alcohol exposure and autonomic nervous system dysfunction: A review article

88%

Jurczyk M., Dyląg K. A., Skowron K., Gil K., Jurczyk M., Dyląg K. A., Skowron K., Gil K.

Folia Medica Cracoviensia

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2019

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vol. 59

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issue 3

7

Interval hypoxic training in complex treatment of Helicobacter pylori-associated peptic ulcer disease

88%

Semen K. O., Yelisyeyeva O. P., Kaminskyy D. V., Cherkas A. P., Zarkovic K., Lutsyk O., Cipak A., Jaganjac M., Zarkovic N.

Acta Biochimica Polonica

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2010

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vol. 57

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issue 2

199-208

EN

This study was aimed to demonstrate the efficacy of interval hypoxic training (IHT) in complex treatment of Helicobacter pylori-associated duodenal peptic ulcer disease (DPUD) by parameters of aerobic metabolism and indexes of heart rate variability (HRV). Eighty patients with H. pylori-associated DPUD were included into the study, mean age 32±1.8 yrs, duration of the disease up to 10 years (66.3 %). IHT was modulated using Frolov's hypoxicator (TDI-01) for 30 days after standard eradication therapy. Daily hypoxic sessions consisted of three one-minute sessions, one two-minute, and one three-minute sessions separated by one-minute intervals of room-air breathing. Use of IHT resulted in more efficient elimination of clinical symptoms, histological hallmarks of inflammation and signs of oxidative stress in glandulocytes of the gastric mucosa as determined by 4-hydroxynonenal accumulation. Moderate prooxidant activity of IHT was demonstrated by the increased level of TBARS and oxidatively modified products, normalization of hydroperoxides, middle mass molecules and atherogenic beta-lipoproteins with simultaneous increase in catalase activity and mild decline of SOD activity. Therefore, IHT appeared to be accompanied by higher intensity of redox reactions and enhanced regeneratory processes in cells and tissues. Significant increase in HRV was also noted. Such changes were associated with reduction of inflammation signs and modulation of the autonomic homeostasis in DPUD patients. In general, use of IHT in complex treatment of H. pylori in DPUD patients can be recommended to increase resistance to oxidative stress and to modulate autonomic balance and oxidative homeostasis.

8

Past strong experiences determine acute cardiovascular autonomic responses to acoustic stress

75%

Jurczyk M., Boryczko A., Furgała A., Poniatowski A., Surdacki A., Gil K., Jurczyk M., Boryczko A., Furgała A., Poniatowski A., Surdacki A., Gil K.

Folia Medica Cracoviensia

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2020

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vol. 60

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issue 4

9

Comparison of multiband filtering, empirical mode decomposition and short-time fourier transform used to extract physiological components from long-term heart rate variability

75%

Adamczyk K., Polak A. G., Adamczyk K., Polak A. G.

Metrology and Measurement Systems

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2021

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vol. 28

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issue 4

10

Cardiovascular response to different types of acute stress stimulations

75%

Jarczewski J., Furgała A., Winiarska A., Kaczmarczyk M., Poniatowski A., Jarczewski J., Furgała A., Winiarska A., Kaczmarczyk M., Poniatowski A.

Folia Medica Cracoviensia

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2019

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vol. 59

|

issue 4

11

Heart rate variability based assessment of cognitive workload in smart operators

71%

Digiesi S., Manghisi V. M., Facchini F., Klose E. M., Foglia M. M., Mummolo C., Digiesi S., Manghisi V. M., Facchini F., Klose E. M., Foglia M. M., Mummolo C.

Management and Production Engineering Review

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2020

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vol. 11

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issue 3

12

Diving and autonomic cardiovascular system regulation in persons with paraplegia

63%

Graczyk D.

Medical Rehabilitation

|

2010

|

vol. 14(1)

25-29

PL

Wstęp: Nurkowanie staje się popularną formą aktywności wśród osób niepełnosprawnych, stwarzającą szczególne warunki oddziaływania rehabilitacyjnego. Korzystnie wpływa na zdolności ruchowe i stan psychiczny. W środowisku wodnym fizyczne ograniczenia zmniejszają się, a niepełnosprawni odkrywają nowe możliwości ruchowe własnego ciała. W piśmiennictwie brak jest wystarczających informacji o wpływie nurkowania na różne aspekty fizjologii osób niepełnosprawnych, w tym na autonomiczną regulację czynności układu krąŜenia u osób z uszkodzeniem rdzenia kręgowego. Cel: Zbadanie czy nurkowanie wpływa na równowagę współczulno-przywspółczulną układu autonomicznego u osób z uszkodzeniem rdzenia kręgowego z następową paraplegią. Materiał i metody: Badanie obserwacyjne, seria przypadków. 19 mężczyzn z paraplegią zbadano podczas dwóch odbywających się w wodach otwartych 20-minutowych nurkowań w skafandrach mokrych na głębokość 6 metrów. Badanie obejmowało okres 10 minut przed i 10 minut po 2 rodzajach nurkowania: turystycznym i zadaniowym. Parametry zmienności rytmu zatokowego serca pozyskano za pomocą sport testera Polar Vantage. Wyniki: Nie wykazano istotnego wpływu nurkowania na zmienność rytmu serca. Ujawniono jednak występowanie różnic międzyosobniczych. Wnioski: Nie potwierdzono niekorzystnego wpływu nurkowania na równowagę autonomiczną badanych, jednak występujące różnice międzyosobnicze nakazują ostroŜność w kwalifikowaniu do nurkowania osób z paraplegią.

EN

Background: Diving has become popular among individualss with various kinds of disabilities and may be applied as a rehabilitation method. This form of activity has a beneficial effect on movement abilities and the psychological state. Some physical limitations disappear under water enabling disabled persons to discover new possibilities for their bodies. Yet there is not enough information - about the influence of diving on different aspects of physiology in disabled persons, in particular about sympathetic-parasympathetic balance in cardiovascular system regulation.Aim: To investigate whether diving can influence heart rate variability (HRV) in individuals with paraplegia.Material and methods: In the case series study 19 men with paraplegia were examined during the couse of two 20-minute, 6 meters deep open water dives in wet suits. There were two phases of the investigation: 10 minutes before and 10 minutes after diving. Two kinds of diving were tested: tourist and task diving. HRV parameters measured before and after diving were obtained by means of the sport-tester Polar Vantage .Results: There were no significant changes in heart rate variability after diving but interindividual differences were shown.Conclusions: The unfavourable influence of diving on balance in the autonomic regulation of the cardiovascular system was not confirmed but due to interindividual differences one is unable to foresee heart rate variability changes in persons with paraplegy during diving.

13

Wpływ procesu starzenia się układu autonomicznego na przebieg najczęstszych chorób układu krążenia

63%

Jabłeka A.

Annales Academiae Medicae Silesiensis

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2009

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vol. 63

|

issue 3

60-66

EN

Aging of autonomic system concerns both sympathetic and parasympathetic part. The process contains structural changes of the neuronal body and terminations and changes of the expression of membrane and intracellular proteins and results in decrease of neural plasticity and regeneration of neurons of autonomic ganglions. Superiority of sympathetic over parasympathetic system is observed in the range of chronotropic regulation of sinus and baroreceptor refl ex. The mechanisms attributed to aging modulate pathophysiological processes in which autonomic system plays an important role. Increased sympathetic activation is observed in chronic heart insuffi cienty which is associated with the increase of the sudden death risk. Activation of autonomic system play also essential role in the pathogenesis of hypertension, atrial fi brillation and orthostatic hypotony. Dysfunction of autonomic system worsens the quality of life in elderly.

PL

Fizjologiczny proces starzenia układu autonomicznego obejmuje zarówno jego komponentę współczulną, jaki i przywspółczulną. Dotyczy szeregu przemian strukturalnych w obrębie ciała neuronu i zakończeń nerwowych, a także wiąże się ze zmianą ekspresji szeregu białek błonowych i wewnątrzkomórkowych. Efektem tych przemian jest ograniczenie plastyczności i zdolności do regeneracji neuronów zwojów układu autonomicznego. U osób w podeszłym wieku obserwuje się przewagę komponenty współczulnej nad przywspółczulną w zakresie regulacji chronotropizmu węzła zatokowo-przedsionkowego i przestrojenie odruchu z baroreceptorów na wyższy poziom. Powyższe zmiany związane z procesem starzenia mogą modulować szereg procesów patofi zjologicznych, w których układ autonomiczny odgrywa istotną rolę. W przebiegu przewlekłej niewydolności serca obserwuje się nadmierną aktywację komponenty współczulnej układu autonomicznego i związany z tym wzrost ryzyka nagłego zgonu. Również w przebiegu nadciśnienia tętniczego, utrwalonego migotania przedsionków oraz w przypadku występowania hipotonii ortostatycznej aktywacja układu autonomicznego pełni istotną funkcję. Występowanie zaburzeń układu autonomicznego w podeszłym wieku niekorzystnie wpływa na jakość życia chorych.

Refine search results

Analysis of heart rate variability during head-up tilt-test in patients with vasovagal syncope

Cardiopulmonary resonance at 0.1 Hz demonstrated by averaged Lomb-Scargle periodogram

Characteristics of autonomic nervous system function in individuals after spinal cord injury

Analysis of heart rate variability during head-up tilt-test in patients with vasovagal syncope

The influence of montelukast on the autonomic nervous system activity in rats with cyclophosphamide-induced hemorrhagic cystitis

Prenatal alcohol exposure and autonomic nervous system dysfunction: A review article

Interval hypoxic training in complex treatment of Helicobacter pylori-associated peptic ulcer disease

Past strong experiences determine acute cardiovascular autonomic responses to acoustic stress

Comparison of multiband filtering, empirical mode decomposition and short-time fourier transform used to extract physiological components from long-term heart rate variability

Cardiovascular response to different types of acute stress stimulations

Heart rate variability based assessment of cognitive workload in smart operators

Diving and autonomic cardiovascular system regulation in persons with paraplegia

Wpływ procesu starzenia się układu autonomicznego na przebieg najczęstszych chorób układu krążenia