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Effect of perioperative glutamine administration on C-reactive protein and liver function tests in patients undergoing hepatic resection

100%

Richard V., Dahiya D., Kaman L., Raj P., Behera A.

Polish Journal of Surgery

2015

vol. 86

issue 1

11-16

Hepatic resections are commonly associated with high morbidity and mortality. Nutrition plays an important role in reducing postoperative complications besides improvement in intensive care and perioperative management. The aim of the study was to evaluate the role of glutamine as an immunonutrient in patients undergoing hepatic resection. Material and methods. The study included 22 patients who underwent hepatectomy. Patients were randomized into two equal groups wherein group A patients received perioperative glutamine whereas group B patients served as controls. Primary outcome measures were level of serum albumin, C‑reactive protein (CRP), liver function tests and absolute neutrophil counts in the postoperative period while secondary outcome included post operative complications. Results. Glutamine decreased the CRP response in liver resection in a statistically significant manner (p=0.028) on the fifth post operative day. This may signify that glutamine decreases the post operative inflammatory response associated with liver resection. Glutamine did not have any significant effect on liver function tests. Postoperative morbidity was less in patients who received glutamine. Conclusion. Glutamine successfully blunted the CRP response in patients who received glutamine postoperatively. Decrease in morbidity following glutamine administration is an attractive area of prospective research and requires further consideration involving larger patient groups.

Is Long Term Creatine and Glutamine Supplementation Effective in Enhancing Physical Performance of Military Police Officers?

75%

Lázaro da Silveira C., Paiva de Souza T. S., Batista G. R., Targino de Araújo A., Gomes da Silva J. C., Cirilo de Sousa M. d. S., Marta C., Garrido N. D.

Journal of Human Kinetics

2014

vol. 43

issue 1

131-138

The objective of this study was to analyze the effect of supplementation with creatine and glutamine on physical fitness of military police officers. Therefore, an experimental double blind study was developed, with the final sample composed by 32 men randomly distributed into three groups: a group supplemented with creatine (n=10), glutamine (n=10) and a placebo group (n=12) and evaluated in three distinct moments, in an interval of three months (T1, T2 and T3). The physical training had a weekly frequency of 5 sessions x 90 min, including strength exercises, local muscular resistance, flexibility and both aerobic and anaerobic capacity. After analyzing the effect of time, group and interaction (group x time) for measures that indicated the physical capabilities of the subjects, a significant effect of time for the entire variable was identified (p<0,05). However, these differences were not observed when the univaried intragroups and intergroups analysis was performed (p>0,05). In face of the results it was concluded that supplementation with creatine and glutamine showed no ergogenic effect on physical performance in military police officers.

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1 Journal of Human Kinetics

1 Polish Journal of Surgery

2 2014

1 Batista G. R.

1 Behera A.

1 Cirilo de Sousa M. d. S.

1 Dahiya D.

1 Garrido N. D.

1 Gomes da Silva J. C.

1 Kaman L.

1 Lázaro da Silveira C.

1 Marta C.

1 Paiva de Souza T. S.

1 Raj P.

1 Richard V.

1 Targino de Araújo A.

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Effect of perioperative glutamine administration on C-reactive protein and liver function tests in patients undergoing hepatic resection

Is Long Term Creatine and Glutamine Supplementation Effective in Enhancing Physical Performance of Military Police Officers?