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Flaremetric evaluation of blood-aqueous barrier breakdown in diabetic patients after phacoemulsification and intraocular lenses with or without heparin-coated surface implantation

100%
Górnik A., Jurowski P.
OphthaTherapy
|
2020
|
vol. 7
|
issue 2
85-89
EN
Background: This study compared the intensity of blood-aqueous barrier breakdown in diabetic patients after phacoemulsification with heparin surface-modified and non-modified intraocular lens (IOL) implantation. Material and methods: In this prospective trial, 68 diabetic patients were enrolled and divided into two groups: 33 patients with heparin surface-modified IOL implants (group 1) and 35 patients with standard hydrophobic IOL implants (group 2). Blood-aqueous barrier breakdown was assessed using a Laser Flare Meter 1 day, 7 days, 14 days, 1 month, and 3 months postoperatively. Results: On postoperative days 1 and 7, the mean flare value was significantly higher in group 2 compared with group 1. On day 14, the mean flare value in both groups was similar and then higher in group 2. Conclusions: The implantation of foldable heparin-coated IOLs led to a lower intensity and faster recovery of blood-aqueous barrier breakdown postoperatively.
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The impact of inflammatory flares in dry eye disease

88%
Izdebska J., Samelska K.
OphthaTherapy
|
2023
|
vol. 10
|
issue 3
179-182
PL
Dry eye disease is a condition treated commonly by most of the ophthalmologists. The current understanding of the disease puts impact on its newly discovered components – ‘flares’. Flares are defined as exacerbations of dry eye disease. They take place in response to the triggers, which may be environmental or internal factors. During the ‘flare’ the immunological response is being activated and the patients experience the worsening of the symptoms. The introduction of the anti-inflammatory treatment (e.g. topical hydrocortisone solution) is the effective treatment in the cases of inflammatory state exacerbations.
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