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An infrared-based device for non-invasive monitoring of eyelid movement during sleep

100%
Wojewnik P., Żmigrodzki J.
Polish Journal of Medical Physics And Engineering
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2013
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vol. 19
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issue 2
85-91
EN
The increased movement of eyes and eyelids is characteristic of the rapid eye movement (REM) sleep stage, making it an important indicator in sleep monitoring. A device was designed to detect this activity in a non-invasive way by means of measuring infrared light intensity reflected off the eyelid. The system converts the light intensity into current through a photodetector, performs analog signal processing and analog to digital conversion (ADC). The data is transmitted wirelessly to a computer, where the results can be displayed, stored and analyzed with a dedicated software, which also provides control over the device. The hardware is embedded in a mask, which is put over the patient's eyes. User safety in terms of mechanical, electrical and optical dangers has been ensured. The device was tested on a napping subject.
2
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Influence of antlerogenic stem cells on the healing of lesions in the corneal epithelium and corneal stroma in rabbits

86%
Kiełbowicz M., Kuropka P., Cegielski M., Kiełbowicz Z., Trębacz P., Hebel M., Aleksiewicz R., Kiełbowicz M., Kuropka P., Cegielski M., Kiełbowicz Z., Trębacz P., Hebel M., Aleksiewicz R.
Polish Journal of Veterinary Sciences
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2020
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vol. 23
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issue 2
3
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The influence of heavy metals on cataracts

86%
Rektor K., Kamiński P., Lorek M., Malukiewicz G., Bogdzińska M., Brodzka S.
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2020
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vol. 33
26-37
EN
Currently, much attention is paid to the search for the etiology of many eye diseases. It has been shown that environmental pollution with heavy metals (cadmium, lead, mercury) is of significant importance. One of these diseases is cataract, i.e. clouding of the lens of the eye. It turns out that heavy metals are deposited in the tissues of the eyes, damaging them and accelerating the disease. This work is aimed at presenting the problem of the influence of heavy metals on cataracts. The study compares the concentration of heavy metals between the control group (81 healthy volunteers) and the group of cataract patients (72 sick). Plasma was used in the research and the ICP-MS method was used.
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Kinetics of increased generation of ·NO in endotoxaemic rats as measured by EPR.

86%
Plonka P. M., Chlopicki S., Wisniewska M., Plonka B. K.
Acta Biochimica Polonica
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2003
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vol. 50
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issue 3
807-813
EN
Ferrous-diethyldithiocarbamate (Fe(DETC)2) chelate is a lipophilic spin trap developed for g·NO detection by electron paramagnetic resonance (EPR) spectroscopy. Using this spin trap we investigated the kinetics of ·NO production in endotoxaemia in rats induced by lipopolysaccharide (Escherichia coli, 10 mg/kg). The NO-Fe(DETC)2 complex was found to give a characteristic EPR signal, and the amplitude of the 3rd (high-field) component of its hyperfine splitting was used to monitor the level of ·NO. We found that in blood, kindey, liver, heart and lung ·NO production starts to increase as early as 2 h after LPS injection, reaches the maximum 6 h after LPS injection and then returns to basal level within further 12-18 h. Interestingly, in the eye bulb the maximum of ·NO production was detected 12 h after LPS, and the signal was still pronounced 24 h after LPS. In brief, the highly lipophilic exogenous spin trap, Fe(DETC)2 is well suited for assessment of ·NO production in endotoxaemia. We demonstrated that the kinetics of increased production of ·NO in endotoxaemic organs, with the notable exception of the eye, do not follow the known pattern of NOS-2 induction under those conditions. Accordingly, only in early endotoxaemia a high level of ·NO is detected, while in late endotoxaemia ·NO detectability is diminished most probably due to concomitant oxidant stress.
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