Search results

Search:
in the keywords: executive dysfunction

Sort By:

Limit search:

Evaluation of the effectiveness of electroencephalographic training with neurofeedback (EEG-NFB) for a patient with dysexecutive syndrome after neurosurgery of two brain aneurysms detected after COVID-19 disease

100%

Morga R., Mirski A., Buczaj A., Pąchalska M.

vol. 21(3)

279-303

The purpose of this study is to evaluate the effectiveness of functional neuromarker- based electroencephalographic training with neurofeedback (EEG-NFB) for a patient with dysexecutive syndrome following neurosurgical operation of two brain aneurysms of the left and right middle cerebral artery (MCA) detected after COVID-19 disease. A right-handed, 56-years-old, not vaccinated, patient, became infected with SARS- CoV-2 and contracted COVID-19 with the manifestation of respiratory symptoms, high fever, dyspnea and low saturation of 79% Sa02. She was hospitalized at the Infectious Disease Unit, where a positive RT PCR test for COVID-19 was confirmed. The acute phase of COVID-19, during which oxygen therapy was administered, lasted two weeks and was complicated by brain fog and transient hypertension (175/100). There were no signs of focal damage to the central nervous system. She was discharged home in a good general and neurological condition. After returning home, the patient was unable to cope with daily functioning, as she said her brain fog continued to persist, manifesting itself as executive dysfunction. Eight weeks after the infection, the patient's neuropsychiatric condition worsened. On CT and MRI examination of the cerebral vessels, she was diagnosed with the presence of two aneurysms located on the left and right middle cerebral arteries (MCA). She was operated on at the Department of Neurosurgery and Neurotraumatology, where a pterional craniotomy and clipping of both brain aneurysms was performed. The Yasargil titanium clip was placed on the aneurysm neck. During the surgery procedures, performed two months apart, there were no signs of a history of subarachnoid haemorrhage and the post-operative period was uneventful, except for a drooping right-eye eyelid (after the second surgery) with a tendency to improve. Each time, the patient was mobilized and walked independently and was discharged home in a good general condition, with no neurological symptoms, except for executive dysfunction. Approximately five months after the SARS-CoV-2 infection (four weeks after the second surgery), her executive dysfunction worsened. Neuropsychological testing using Mindstreams™ Interaction Computer Tests revealed moderate Dysexecutive Syndrome (DES), while neurophysiological testing using qEEGs, ERPs and sLORETA tomography, a functional neuromarker of frontotemporal area dysfunction. The EEG pattern was characterized by excessive, slow (about 6 Hz) activity in frontotemporal areas, which indicated the progressive loss of cognitive control over time. The patient was offered an electroencephalographic training protocol with neurofeedback (EEG-NFB) based on the detected functional neuromarker, which reduced DES. The improvement achieved during therapy was statistically significant [compared to the normative database (Human Brain Index, HBI)]. In effect, the patient's quality of life improved, as she herself pointed out. Her symptoms of brain fog and DES disappeared and she returned to her previous work as a waitress. The Human Brain Index (HBI) methodology can be successfully used in the neurodiagnosis and implementation of individualized electroencephalographic training with neurofeedback (EEG-NFT) for patients with executive dysfunction after contracting longCOVID.

Event-related potentials as an index of lost cognitive control and lost self in a TBI patient with duration increasing post-traumatic Delusional Misidentification Syndrome concluded with Cotard Syndrome

63%

Pąchalska M.

vol. 17(4)

487-508

The goal of the study was twofold: 1) to evaluate the QEEG/ ERPs indexes of functional brain impairment in a TBI patient diagnosed with chronic lost cognitive control and lost self caused by post traumatic, and here increasing over time, delusional misidentification syndrome concluded with Cotard syndrome in the blooming stage, with nihilistic delusions concerning the body and existence, and the delusion of being dead, and 2) to explore the mind of a patient whose identity has been disengaged, and who experiences the loss of his self and relations with his immediate surroundings with all the tragic consequences that entails. I herein present a 52-year-old patient, who – after a serious head injury due to a car accident 20 years ago, which re- sulted in focal injuries in the frontal and temporal areas of the right hemisphere – developed Cotard syndrome. After arousal from a 63-day coma and 98 days of post-traumatic amnesia, he manifested: (1) the loss of autobiographical memory, (2) a lost self, (3) forgotten family ties (including his lover). The study revealed that the patient’s cognitive control system is completely destroyed: no cognitive components have been found. Recall from memory has been completely disturbed (a low amplitude of N170). The two hemispheres work inco- herently with the right hemisphere revealing a serious delay in memory recall.

Refine search results

2 Acta Neuropsychologica

1 2023

1 2019

2 Pąchalska M.

1 Buczaj A.

1 Mirski A.

1 Morga R.

Search results

Evaluation of the effectiveness of electroencephalographic training with neurofeedback (EEG-NFB) for a patient with dysexecutive syndrome after neurosurgery of two brain aneurysms detected after COVID-19 disease

Event-related potentials as an index of lost cognitive control and lost self in a TBI patient with duration increasing post-traumatic Delusional Misidentification Syndrome concluded with Cotard Syndrome