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Objective: The objective of the study was to present the methodology and interpretation of the results of distortion-product otoacoustic emission phase shift (Shift-DPOAE) measurements in healthy subjects and patients with Meniere’s disease in remission or during the attack. Material and methods: Shift-DPOAE measurements were performed in two healthy subjects with no otological or neurological problems as well as in six patients diagnosed with Meniere’s disease. Results obtained from all eight subjects are presented. Detailed otoscopy, impedance audiometry, pure tone audiometry, DPOAE, and Shift-DPOAE tests were performed in all subjects. Results: Normal results of Shift-DPOAE measurements obtained from two healthy subjects as well as normal (two subjects) and abnormal (four subjects) Shift-DPOAE results obtained from patients with Meniere’s disease are presented in order to thoroughly discuss the methodology and interpretation of Shift-DPOAE measurements. Conclusions: Shift-OAE is a promising diagnostic tool with a great clinical potential for diagnostics and monitoring of Meniere’s disease in patients whose hearing has not yet been damaged. The test is completely non-invasive and can be carried out immediately after the onset of disease attack with symptoms still present at the time of the test; in addition, the procedure takes just several minutes.
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