Search results

1

Clostridium difficile infection in patients hospitalized in the gastroenterology ward – retrospective analysis

100%

Podlaszewska K., Ewa M. P., Gąsiorowska A.

Polish Journal of Surgery

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2018

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vol. 90(1)

7-12

EN

INTRODUCTION. Clostridium difficile associated colitis became over last years a worldwide medical issue. It involves patients of the Polish hospitals too. The aim of the study was the analysis of CDAD incidence and the course of infection in Gastroenterology Ward of Regional Specialist Hospital of Zgierz, 2012-2015. MATERIAL AND METHODS. Retrospective analysis of the medical documentation of 79 patients with CDAD was performed. Demographic and epidemiological data and the clinical course of infection were analyzed. RESULTS. The study group comprised of women in 59,5% and men in 40,5%. The patients’ average age was 70,5 years. The average hospitalization period was 10,3 days. CDAD infection seasonality was proved, with statistically significant peak in springtime. 73% of patients were previously hospitalized and 85% - had co-morbidities. 76% of patients underwent antibiotherapy, whilst 29% - used PPI prior to CDAD diagnosis. 50,6% of patients had severe CDAD diagnosed. The recurrence reached 14%. In 19% of patients CDAD resulted in death. DISCUSSION. The results of the study confirm increase of the incidence of the patients with CDAD in Gastroenterology Ward over 4-years’ observation. The prevalence was higher among 65+ patients, after prior hospitalization and antibiotherapy. The co-morbidities was a significant risk factor, especially common in severe cases. CONCLUSION. The results we obtained confirm substantial importance of Clostridium difficile infection leading to antibiotherapy-associated diarrhea among adults, causing prolonged hospitalization, increased prevalence and mortality of patients. Getting to know and minimizing the risk factors will prevent the future outbreak of the disease.

2

Effects of porcine epidemic diarrhea virus infection on tight junction protein gene expression and morphology of the intestinal mucosa in pigs

88%

Zong Q. F., Huang Y. J., Wu L. S., Wu Z. C., Wu S. L., Bao W. B., Zong Q. F., Huang Y. J., Wu L. S., Wu Z. C., Wu S. L., Bao W. B.

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2019

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issue 2

3

Effect of combinations of intravenous small-volume hypertonic sodium chloride, acetate Ringer, sodium bicarbonate, and lactate Ringer solutions along with oral fluid on the treatment of calf diarrhea

88%

Aydogdu U., Yildiz R., Guzelbektes H., Naseri A., Akyuz E., Sen I.

Polish Journal of Veterinary Sciences

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2018

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vol. 21

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issue 2

4

Safety of oral nifuroxazide – analysis of data from a spontaneous reporting system

88%

Karlowicz-Bodalska K., Głowacka K., Boszkiewicz K., Han S., Wiela-Hojeńska A.

Acta Poloniae Pharmaceutica - Drug Research

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2019

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vol. 76

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issue 4

745-751

EN

Nifuroxazide is a popular chemotherapeutic agent, that is widely used in Poland in acute and chronic bacterial diarrhea treatment. It is available in pharmacies as over-the-counter tablets for adults and a suspension on prescription for children. The aim of the study was to assess the safety of nifuroxazide therapy. Adverse reaction reports from the Regional Pharmacovigilance Center in Wroclaw, the pharmaceutical company PPF Hasco-Lek, and VigiAccess and EudraVigilance databases were analyzed. Based on the analysis of the data collected from the above sources, nifuroxazide have shown a high therapeutic value in the gastrointestinal tract infections, maintaining high safety of usage at the same time. The number of drug application adverse reactions in Poland is not so high primarily due to high safety profile and low patient awareness of the possibility of reporting drug side effects.

5

Ultrasound findings in extragenital endometriosis

88%

Dong Y., Braden B., Klinger C., Ripolles T., Dietrich C. F.

Journal of Ultrasonography

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2018

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vol. 18

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issue 74

247-254

EN

We present a report on ultrasound findings in extragenital endometriosis and a literature review accompanied by illustrations. Intestinal endometriosis should be considered in female patients of reproductive age who present with constipation, gastrointestinal bleeding, nausea, vomiting, cramp-like abdominal pain, diarrhoea and pelvic pain. Although definitive preoperative diagnosis of endometriosis is difficult, clinical suspicion and appropriate imaging might prevent extensive surgical procedures with higher morbidity. Contrast-enhanced ultrasound is an efficient non-invasive imaging method without any radiation exposure that supports the early diagnosis of intestinal endometriosis and may help assess the vascularization of endometriotic lesions within the distinct layers of the intestinal wall.

PL

Autorzy przedstawiają sprawozdanie dotyczące badań ultrasonograficznych przeprowadzonych u pacjentek z endometriozą zlokalizowaną poza narządami rozrodczymi wraz z przeglądem piśmiennictwa poparte przykładami klinicznymi. U pacjentek w wieku rozrodczym, u których występują zaparcia, krwawienie z przewodu pokarmowego, nudności, wymioty, bolesne skurcze brzucha, biegunka i ból w obrębie miednicy mniejszej należy rozważyć endometriozę jelitową. Choć postawienie ostacznego rozpoznania przedoperacyjnego jest trudne, wysunięcie klinicznego podejrzenia oraz odpowiednie badania obrazowe mogą pozwolić na uniknięcie rozległego zabiegu chirurgicznego obarczonego wyższą częstością powikłań. Badanie ultrasonograficzne z użyciem środka kontrastującego to skuteczna i nieinwazyjna metoda obrazowania, która nie wiąże się z narażeniem pacjentki na promieniowanie oraz która może zasugerować wczesne rozpoznanie endometriozy jelitowej i pomóc w ocenie unaczynienia zmian endometrialnych w obrębie poszczególnych warstw ściany jelita.

6

Prevalence of pathogenicity island ETT2 in Escherichia coli isolated from piglets with diarrhea in northeast of China

75%

Yuan C. W., Liu W. X., Hou J. L., Zhang L. G., Wang G. Q.

Polish Journal of Veterinary Sciences

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2018

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vol. 21

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issue 1

7

Cryptosporidiosis outbreak on a dairy farm: Detection of Cryptosporidium parvum as a causative agent in the water source

75%

Karakavuk M., Can H., Döşkaya M., Karakavuk T., Erkunt-Alak S., Köseoğlu A. E., Gül A., Ün C., Gürüz Y., Değirmenci-Döşkaya A., Karakavuk M., Can H., Döşkaya M., Karakavuk T., Erkunt-Alak S., Köseoğlu A. E., Gül A., Ün C., Gürüz Y., Değirmenci-Döşkaya A.

Polish Journal of Veterinary Sciences

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2021

8

Intussuception at Atypical Ages in Children and Adults - 11 Years Experiences

63%

Peyvasteh M., Askarpour S., Javaherizadeh H., Beigom Al-Taha B.

Polish Journal of Surgery

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2011

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vol. 83

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issue 6

304-309

EN

Intussusception is a curious anatomic condition characterized by the invagination of one segment of the gastrointestinal tract into the lumen of an adjacent segment. Once initiated, additional intestinal telescopes into the distal segment, causing the invaginated intestine to propagate distally within the bowel lumen.The aim of the study was to evaluate the clinical manifestation, etiology, and outcome of intussuception at atypical ages.Material and methods. This retrospective study was carried out on patients aged <6 mo or >2 yr with intussusception. Duration of study was from March, 20, 1997 to March, 20, 2008. The places of study were Imam Khomeini and Abuzar referrals hospital. Cases were classified according to age and sex. According to age, patients were <6 mo, 2-10 years, 10-18, and more than 18 years. Age, sex, history, chief complaint, clinical manifestation, sonographic findings, duration of clinical manifestation, method of treatment, outcome, duration of hospital staying, and ICU admission were studied. Data were analyzed with SPSS ver 16 (Chicago, IL, USA) and Epi-info.Results. In this study, 36 cases with diagnosis of intussusception at atypical ages, <6 mo or >2 yr, were included. From all cases, 21 cases (58.3%) were 2 through 10 years and male: female ratio was 2.26:1. Ten cases (27.8%) had history of medical condition. Eighty percent (29 cases) had abdominal pain and 20 cases (58.3%) had vomiting. Abdominal mass was found in 14 cases (38.8%). Sonography was done for 30 (83.3%) of cases and suggesting intussuception in 25 (69.4%) of cases. Intussuception was reduced by hand and performed appendectomy for 10 cases (27.8%). Bowel resection was done for 19 cases (52.8%) and radiological reduction was done for 2 cases (5.6%). Eighteen (50%) cases had anemia. Twenty-five cases admitted to ICU. One (2.8%) patient died (a 65 year old woman). Appendicitis is the most common well defined injury associated with intussusception.Conclusion. This study showed that with advancing age, incidence of intussusception will be decreased. As age increasing, rate of bowel resection will be increased. All cases with appendectomy and reduction by hand had hospital staying 3-10 days. The results of this study was similar to other studies. The most widely used diagnostic procedure for intussusception was sonography.

9

Zakażenia żołądkowo-jelitowe o etiologii norowirusowej

63%

Kalicki B., Furgał J., Maślany A., Bartoszewicz L., Jung A.

Pediatria i Medycyna Rodzinna

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2010

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vol. 6

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issue 4

283-286

EN

Noroviruses – members of the family Caliciviridae – are one the most common factors of gastrointestinal infections. For nearly half a century, when the symptoms caused by these microorganisms were first described, knowledge on this subject has been systematically growing. The paper presents the contemporary knowledge on the structure, routes of transmission and symptoms of illness caused by noroviruses. In the thesis we also present the methods of prevention and treatment in gastroenteritis caused by noroviruses. As noroviruses have high infectivity and resistance to typically used detergents, the effective protection against infection is very difficult. Symptoms appear within 2 days after infection, initially starting with nausea and vomiting, then accompanied by watery diarrhea. Among the currently used diagnostic methods – that is electron microscopy, enzyme immunoassay and RT-PCR – for the most optimum is considered the latter. There is no specific treatment of noroviral infections or primary prevention in the form of vaccination. Treatment is based on using rehydrating and rebalancing fluids, helping with electrolyte disturbances, in the form of oral or intravenous administration. The disease course is usually self-limiting and does not give long-term complications. More severe and prolonged course of disease is observed among children, the elderly and people with compromised immune systems. Taking into account the microbiological characteristic of noroviruses and the lack of specific treatment, in the coming years we expect an increase in incidence of acute gastroenteritis of this aetiology.

PL

Norowirusy – klasyfikowane do rodziny Caliciviridae – należą do najczęstszych czynników epidemiologicznych zakażeń żołądkowo-jelitowych. Od niemal pół wieku, kiedy po raz pierwszy opisano objawy choroby powodowanej przez te drobnoustroje, wiedza na ich temat systematycznie rośnie. W pracy przedstawiono aktualne informacje o budowie, drogach zakażenia i symptomach chorobowych powodowanych przez norowirusy oraz metody zapobiegania i leczenia zakażeń przez nich wywoływanych. Z uwagi na wysoką zakaźność oraz odporność norowirusów na standardowo stosowane detergenty skuteczna ochrona przed zakażeniem jest bardzo trudna. Objawy chorobowe pojawiają się w ciągu 2 dni od zarażenia, do nudności i wymiotów dołącza się wodnista biegunka. Wśród obecnie stosowanych metod diagnostycznych, czyli mikroskopii elektronowej, testów immunoenzymatycznych oraz RT-PCR, za optymalną uznawana jest ta ostatnia. Nie istnieje przyczynowe leczenie zakażeń norowirusowych ani profilaktyka pierwotna w postaci szczepień ochronnych. Leczenie polega na stosowaniu płynów nawadniających oraz wyrównujących zaburzenia elektrolitowe i kwasowo-zasadowe – w postaci doustnej i dożylnej. Przebieg choroby jest najczęściej samoograniczający się, zazwyczaj nie daje ona odległych powikłań. Bardziej burzliwy i dłuższy przebieg choroby obserwuje się u dzieci, osób starszych oraz z upośledzoną odpornością. Biorąc pod uwagę charakterystykę mikrobiologiczną norowirusów oraz brak możliwości leczenia przyczynowego, w najbliższych latach możemy spodziewać się wzrostu zachorowań o tej etiologii.

10

Porównanie właściwości adsorbentów: smektynu dwuoktanościennego i aktywowanego węgla leczniczego w terapii ostrej biegunki u dzieci

63%

Czerwionka-Szaflarska M., Adamska I., Gawryjołek J.

Pediatria i Medycyna Rodzinna

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2013

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vol. 9

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issue 1

57-59

EN

Acute infectious diarrhea is one of the most common causes of morbidity in the pediatric population, mostly of viral etiology. The disease is usually of self-limited course, and as treatment relievers are recommended. The most important part of the treatment are oral rehydration solutions. In the adjuvant treatment may be considered, inter alia, the use of adsorbents. In Poland, the most widely used adsorbents include activated charcoal and activated smectite. The binding capacity for bacterial toxins of the activated charcoal is not completely established, there is no clinical evidence of this action. In clinical studies the ability of smectite to adsorb viruses and bacterial toxins has been confirmed. Protective effect of smectite for stomach and intestines mucous membrane has also been well documented – because of these unique properties, smectite can be classified as second-generation adsorbent. According to current recommendations of ESPGHAN and ESPID from 2008, smectite is the only adsorbent of proven security, that used together with oral rehydration solutions increases the chances of reducing the duration of diarrhea.

PL

Ostra biegunka infekcyjna jest jedną z najczęstszych przyczyn zachorowań w populacji dziecięcej, najczęściej o etiologii wirusowej. Choroba ma zazwyczaj przebieg samoograniczający się, a w terapii zalecane są leki objawowe. Za najważniejszy element leczenia uznaje się stosowanie doustnych płynów nawadniających. W leczeniu uzupełniającym można rozważyć między innymi stosowanie adsorbentów. W Polsce najczęściej stosowanymi adsorbentami są aktywowany węgiel leczniczy i smektyn dwuoktanościenny. Zdolność wiązania toksyn bakteryjnych przez węgiel leczniczy nie jest w pełni udowodniona, nie ma badań klinicznych potwierdzających to działanie. W badaniach klinicznych potwierdzono zdolność smektynu dwuoktanościennego do adsorbcji wirusów i toksyn bakteryjnych. Udokumentowano również wielokierunkowe działanie ochronne smektynu dwuoktanościennego na błonę śluzową żołądka i jelit – z uwagi na te unikalne właściwości smektyn może być kwalifikowany jako adsorbent drugiej generacji. Zgodnie z aktualnymi zaleceniami ESPGHAN i ESPID z 2008 roku smektyn dwuoktanościenny jest jedynym adsorbentem o udowodnionym bezpieczeństwie stosowania, który zastosowany równolegle z doustnymi płynami nawadniającymi zwiększa szanse na skrócenie czasu trwania biegunki.

11

Practicability of Enteritis – prevention in Trekking and Mountaineering at High Altitude by Systematic Hand Disinfection

51%

Ulmer H.-V., Risse J., Küpper T.

Health Promotion & Physical Activity

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2020

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vol. 13

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issue 4

25-28

EN

Introduction: The hygienic conditions during trekking or mountaineering at high altitudes are reduced, especially regarding defecation and hand hygiene. An additional problem exists in regions above the snowline, especially in highly frequented regions: snow may be contaminated by faecal microbes, causing diarrhea. Prevention against faecal-oral infections must include not only disinfection of drinking water, but hand disinfection, too, e.g. by a water-free hand gel. The practicability of this measure was tested during a Himalaya expedition on the way to Mt. Everest. Material and methods: 10 participants were instructed to use Stokosept-Gel, an alcohol based skin disinfectant, at least prior to meals, after using a toilet and after handling boot-laces and to note each use (including additional occasions). Results: A very good practicability of using the hand gel, which was absorbed quickly (ca. ¼ min) was reported. 100 ml were sufficient for at least 2 weeks and there were no side effects or problems at the skin. During the mountaineering phase which included a total of 250 person days in the field no diarrhea occurred. Conclusion: We conclude that using such hand gels is – additional to other procedures – a very practical prevention against diarrhea in mountaineering at high altitude.

Refine search results

Clostridium difficile infection in patients hospitalized in the gastroenterology ward – retrospective analysis

Effects of porcine epidemic diarrhea virus infection on tight junction protein gene expression and morphology of the intestinal mucosa in pigs

Effect of combinations of intravenous small-volume hypertonic sodium chloride, acetate Ringer, sodium bicarbonate, and lactate Ringer solutions along with oral fluid on the treatment of calf diarrhea

Safety of oral nifuroxazide – analysis of data from a spontaneous reporting system

Ultrasound findings in extragenital endometriosis

Prevalence of pathogenicity island ETT2 in Escherichia coli isolated from piglets with diarrhea in northeast of China

Cryptosporidiosis outbreak on a dairy farm: Detection of Cryptosporidium parvum as a causative agent in the water source

Intussuception at Atypical Ages in Children and Adults - 11 Years Experiences

Zakażenia żołądkowo-jelitowe o etiologii norowirusowej

Porównanie właściwości adsorbentów: smektynu dwuoktanościennego i aktywowanego węgla leczniczego w terapii ostrej biegunki u dzieci

Practicability of Enteritis – prevention in Trekking and Mountaineering at High Altitude by Systematic Hand Disinfection