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Preparation, chemical components and biological activities of essential oil from Licorice seeds

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Qin X., Le L., Jiang F., Yong J., Tian D.
World News of Natural Sciences
|
2024
|
vol. 54
45-57
EN
The essential oil from licorice seeds was prepared and investigated using gas chromatography-mass spectrometry (GC-MS), resulting in the identification of 47 beneficial components. The oil was found to be abundant in fatty acids: including linoleic acid (43.87%), palmitic acid (10.43%), oleic acid (4.51%), stearic acid (1.83%), and palmitoleic acid (1.25%). The oil’s physicochemical properties revealed an acid value of 0.066 mg/g, a peroxide value of 7.267 g/100g, an iodine value of 37.231 g/100g, and a saponification value of 186.823 mg/g, indicating that it can be regarded as a premium edible oil. The antioxidant activity of this oil showed that it has a antioxidant capacity with a free radical scavenging rate of up to 38.53% at a concentration of 15 mg/mL. The in vitro anticancer activities against lung cancer A549 cell lines and cervical cancer Hela cell lines showed that it inhibited the cancer cell lines with cell viability of 61% and 56% at a concentration of 100 mg/mL, respectively with a dose-depedent manner. This results indicate that the oil can be considered to be used as edible oil or potential applications in the field of food and medicine.
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