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Centaurea cyanusL. Polysaccharides and Polyphenols Cooperation in Achieving Strong Rat Gastric Ulcer Protection

100%
Pirvu L., Bubueanu C., Panteli M., Petcu L., Coprean D.
Open Chemistry
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2015
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vol. 13
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issue 1
EN
This work was aimed at testing gastroprotective effects of Centaurea cyanus L. (herba) polysaccharides (P) and polyphenols (A) fractions on stress-induced rat ulcer model. Studies evaluating acute toxicity in rats and antioxidant (chemiluminescence method) and antimicrobial (on Staphylococcus aureus ATCC6538 and Escherichia coli ATCC8739 strains) activities of Centaurea cyanus L. (herba) product, which combined polysaccharides and polyphenols fractions (PA), have also been done. Accordingly, in vivo pharmacological studies revealed high influence of PA product (500 mg kg-1 of body weight) on deep, moderate and superficial gastric mucosal lesions, greater than that of chemical reference, Ranitidine. P product was proven more effective than Ranitidine in opposing the emergence of deep necrotic lesions only, suggesting the ability of polysaccharides compounds to consolidate gastric mucous layer as well as their certain tendency for cooperation with polyphenols fractions. The acute toxicity study indicated the lack of toxicity of PA product and maximum tolerated doses greater than 1875 mg kg-1 of body weight. PA product provided augmented scavenger activity and week antimicrobial activity on Staphylococcus aureus ATCC6538 and Escherichia coli ATCC8739 strains, resulting in better opportunities for valorisation of the aerial part of Centaurea cyanus L. species in order to obtain new and effective natural medicines.
2
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Comparison of chemical composition and biological activities of Seseli rigidum fruit essential oils from Serbia

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Ilić M. D., Jovanović V. P. S., Mitić V. D., Jovanović O. P., Mihajilov-Krstev T. M., Marković M. S., Stojanović G. S.
Open Chemistry
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2015
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vol. 13
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issue 1
EN
Plants from genus Seseli, have been widely used in European traditional medicine, exhibiting antibacterial, antifungal, insect repellent, emmenogogue, antiflatulence, anti-inflammatory, antinociceptive, anti-tumor, antirheumatic activities and protective effect on human lymphocytes DNA. They usually grow on mountain rocky terrains. Part of their habitat on Vidlic Mountain, located in South-east Serbia, was struck with a large wildfire. Seseli rigidum fruit essential oils (from post fire and control areas) compositions were analyzed by GC and GC-MS, identifying monoterpenes α-pinene and sabinene as most abundant. Statistical tests showed a non-significant difference in chemical composition of these two oils, but a significant difference in comparison with the herb from a geographically different origin. Antimicrobial tests showed strong activities of the oils against tested bacteria, thus confirming its administration in various inflammation processes as a quite effective remedy. Applying DPPH. and ABTS+. radical scavenging and total reducing Fe(III) to Fe(II) power assays, antioxidant characteristics of both studied essential oils were estimated as weak, though of close values. Seseli rigidum fruit essential oil was proven as a potent inhibitor of human and horse serum cholinesterase, recognizing its possible application as neural protective agent
3
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Pseudomonas and Pedobacter isolates from King George Island inhibited the growth of foodborne pathogens

88%
Wong C. M. V. L., Tam H. K., Alias S. A., González M., González-Rocha G., Domínguez-Yévenes M.
Polish Polar Research
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2011
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issue 1
4
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Flame Retardant and Antimicrobial Jute Textile Using Sodium Metasilicate Nonahydrate

88%
Basak S., Samanta K. K., Chattopadhyay S. K., Das S., Narkar R., Dsouza C., Shaikh A. H.
Polish Journal of Chemical Technology
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2014
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vol. 16
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issue 2
106-113
EN
Flame retardant and antimicrobial functionalities were imparted in jute textile using sodium metasilicate nonahydrate (SMSN), commonly known as “water glass”. Sodium metasilicate nonahydrate (SMSN) was applied in jute fabric in different concentration by padding method followed by drying. Flame retardancy of the fabric was evaluated by Limiting Oxygen Index (LOI) and burning behaviour under vertical flammability tester including the char length. Burning rate was found to decrease by almost 10 times after an application of 2% SMSN compared to the control sample. Thermogravimetry (TG) and differential scanning calorimetry (DSC) analysis of both the control and treated jute fabrics were utilized to understand the mechanism of developed flame retardance in jute fabric. It was observed that the SMSN treated samples showed excellent antimicrobial property against both gram positive and gram negative bacteria. Antimicrobial properties of both the control and treated jute fabrics were also measured quantitatively.
5
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Antimicrobial activity of petroleum ether and methanolic extracts from fruits of Seseli devenyense Simonk. and the herb of Peucedanum luxurians Tamam.

88%
Widelski J., Grzegorczyk A., Malm A., Chinou I., Głowniak K.
Current Issues in Pharmacy and Medical Sciences
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2015
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vol. 28
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issue 4
257-259
EN
Plants of the Apiaceae family usually contain coumarins. These are used worldwide in traditional medicine, as well as in modern therapeutics. The aim of our study was to determine the antimicrobial activity of four extracts (methanolic and petroleum ether extracts) obtained from two Apiaceae species: Seseli devenyense (fruits) and Peucedanum luxurians (herb). The activity of the investigated extracts was tested against 7 strains of Gram+ bacteria, and 7 strains of Gram-, as well as three of yeast. The results of this show that the best activity of such extracts (specifically, by way of petroleum ether) was seen as being against Staphylococcus aureus strains.
6
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PHYTOCHEMICAL ANALYSIS AND BIOLOGICAL EVALUATION OF FORSSKAOLEA VIRIDIS AERIAL PARTS

88%
El-Bassossy T. A., Ahmed F. A., El-Mesallamy A. M.
Acta Poloniae Pharmaceutica - Drug Research
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2019
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vol. 76
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issue 5
815-823
EN
The chemical investigation of the chloroform and ethyl acetate extracts of the aerial parts of Forsskaolea viridis Ehrenb. ex Webb (Family: Urticaceae) led to isolation eight compounds for the first time from this plant, while two phenolic compounds, identified as p-coumaric and caffeic acids as well as six flavonoid compounds identified as 5-hydroxy-6,7,3',4'-tetramethoxy flavone, chrysoeriol, acacetin, chrysoeriol-7-O-β-D-glucoside, kaempferol-3-O-(2"-O-E--p-coumaroyl)-β-D-glucoside and isovetixin. The chemical structure of the isolated compounds was established by spectroscopic methods including UV, MS, 1H-NMR, and 13C-NMR. Antimicrobial, antioxidant and cytotoxic activities of the ethyl acetate and chloroform extracts were evaluated. The ethyl acetate extract exhibited strong antimicrobial activity (12-30 mm) against the tested strains. The ethyl acetate and chloroform extracts showed fair antioxidant and cytotoxicity.
7
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Inhibition of methicillin resistant Staphylococcus aureus by a plasma needle

88%
Miletić M., Vuković D., Živanović I., Dakić I., Soldatović I., Maletić D., Lazović S., Malović G., Petrović Z., Puač N.
Open Physics
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2014
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vol. 12
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issue 3
160-167
EN
In numerous recent papers plasma chemistry of non equilibrium plasma sources operating at atmospheric pressure has been linked to plasma medical effects including sterilization. In this paper we present a study of the effectiveness of an atmospheric pressure plasma source, known as plasma needle, in inhibition of the growth of biofilm produced by methicillin resistant Staphylococcus aureus (MRSA). Even at the lowest powers the biofilms formed by inoculi of MRSA of 104 and 105 CFU have been strongly affected by plasma and growth in biofilms was inhibited. The eradication of the already formed biofilm was not achieved and it is required to go to more effective sources.
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