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The application of moist dressing in treating burn wound

100%
Wei L.
Open Medicine
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2014
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vol. 10
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issue 1
EN
Basic experiments have demonstrated that the effect of wound healing in moist environments is better than that in dry environments; therefore, research on moist dressing is the focus of wound healing research. 42 burn patients receiving treatment in Jiangsu Provincial People’s Hospital were selected as experimental cases. Wound surface is divided into treatment group and control group using a self-contrasted method. The treatment group received a moist dressing in the treatment of burn wounds and the control group adopted iodine gauze or Vaseline gauze coverage. Wound healing effect and the impact on the degree of pain of in the two different treatment methods were observed after treatment. The results of 42 patients were included in the analysis. The average healing time of patients’ burn wounds in treatment group is (10.9 3.3) d, and the average healing time in control group is (13.8 3.6) d, so, the difference is significant (P<0.01). Wound pain in the treatment group is significantly lower than that in the control group (P<0.01). Using moist dressing (Mepitel and Mepilex, etc.) in the treatment of burn wounds, woundhealing time can be shortened and wound pain can be reduced significantly.
2
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The effects of vitamin E and selenium on blood flow to experimental skin burns in rats using the 133Xe clearance technique

88%
Varoglu E., Seven B., Gumustekin K., Aktas O., Sahin A., Dane S.
Open Medicine
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2010
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vol. 5
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issue 2
219-223
EN
The aim of the present experimental study was to determine and to compare the effects of vitamin E and of selenium on the blood flow to a wound region in rats, using the xenon-133 (133Xe) clearance technique. Burn wounds were made on the right thighs of rats followed by oral administration of vitamin E or selenium for a period of 10 days. The effect of vitamin E and of selenium individually on blood flow in the wound region was assessed before and after oral administration using the 133Xe clearance technique. Both vitamin E and selenium significantly increased the blood flow in the wound region (P<0.05). Our results in rats suggest that both vitamin E and selenium have beneficial effects on the skin wound healing process by increasing the skin blood flow.
3
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How safe is the use of prosthetic materials in the repair of abdominal-wall defects in malnourished subjects?

88%
Karahan M., Kulacoglu H., Seker D., Ergul Z., Kiziltay A., Yilmazer D., Captug O., Yavuz A., Serbetci K., Bilgili H., Hasirci N.
Open Medicine
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2009
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vol. 4
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issue 3
331-336
EN
Incisional hernias and abdominal-wall defects consume large amounts of healthcare resources. Use of mesh is effective in treatment of these disorders and can decrease the rate of recurrence. This experimental study focused on the safety of mesh use in the setting of malnutrition, a condition that impairs wound healing. Rats were divided into two groups: normally fed and food-restricted. An abdominal-wall defect, 2 by 2 cm, was covered with polypropylene mesh, 2.5 by 2.5 cm. After sacrifice of the rats at the 21st and 60th days, tissue samples were sent for tensiometric and histopathological studies. No significant difference in infectious complications was observed between the two groups. Tensiometry revealed no significant differences between the groups. On histopathological examination, the only difference noted was in the vascularization scores of normally fed rats. For malnourished subjects that survived after surgery, the use of polypropylene mesh appeared safe in the closure of abdominal-wall defects, with no increase in infection rate and satisfactory wound healing.
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