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Synthesis, spectral studies and antimicrobial activity of thiosemicarboximide derivatives containing pyridine nucleus

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Patel H., Bhoraniya N., Pankhaniya P., Purohit D. M.
World News of Natural Sciences
|
2024
|
vol. 54
9-16
EN
The Thiosemicarboximide derivatives of (5a-5j) were synthesized by the condensation of Chalcone derivatives (4a-4j) with H2N-NH-CS-NH2 in the presence of glacial acetic acid. The structures of newly synthesized compounds were confirmed based on 1H-NMR, mass spectra, and IR data. All the newly synthesized compounds were screened for their antibacterial activity against Gram +ve Bacteria Bacillus subtilis, Staphylococcus aureus, and Gram –ve Bacteria Escherichia coli, Pseudomonas aeruginosa and Fungi Aspergillus niger.
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