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1

Actual remarks on

100%
Palgan K., Drewa G.
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vol. 47
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issue 3
193-207
EN
The paper presents review of the literature concerning the most recent data on the of , mechanismus involved in , of as well as . A special attention has been drown to the role of the angiogenesis in tumor progression.
2

The role of copper in tumor angiogenesis ? clinical implications

100%
Nasulewicz A., Opolski A.
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EN
This review concerns a brief introduction into the basics of tumor blood vessels development as well as the regulatory mechanisms of this process. The role of copper ions in tumor angiogenesis is discussed. The new antiangiogenic therapies based on a reduction of copper levels in tumor microenvironment are reviewed.
3

Inhibitors of neoangiogenesis in antitumor therapy

88%
Opolski A., Wietrzyk J.
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vol. 55
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issue 3
369-385
EN
The role of angiogenesis in tumor growth and metastasis is discussed. The endogenous activators and inhibitors of tumor angiogenesis are presented and their mechanisms of action are reviewed. An overview on angiogenesis as a new potential targed of antitumor therapy is described. The clinical trials of various antiangiogenic agents are briefly summarized and their differential mechanisms of action are discussed.
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