Search results

1

TLC screening in searching for active components in Rhodiola rosea L. roots

100%

Nikolaichuk H., Choma I. M.

Annales Universitatis Mariae Curie-Skłodowska, sectio AA – Chemia

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2019

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vol. 74

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issue 1

EN

Thin layer chromatography (TLC) has been used for screening analysis of extracts from Rhodiola rosea roots. TLC is a fast, simple and inexpensive screening technique, often used in qualitative analysis of plant substances. The results of TLC analysis confirmed presence of sugars, terpenes, terpenoids, saponines and propylpropanoids in Rhodiola roots. The extracts of Rhodiola rosea revealed strong antioxidant activity.

2

TLC-densitometric analysis of α-escin in bulk drug substance and in pharmaceutical dosage forms

100%

Dolowy M., Pyka-Pajak A., Filip K., Zagrodzka J.

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2015

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vol. 28

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issue 3

186-191

EN

A quite simple and rapid TLC-densitometric method for the identification of α-escin (Aescin) in bulk drug substances was developed. In so doing, different chromatographic conditions, including various mobile and stationary phases, were tested. A TLC densitometric determination of the examined compound was performed without using visualizing reagent, yet with the use of appropriate dipping reagents, in order to obtain reliable UV-densitometric measurements of α-escin - a substance which has weak chromophore groups. Herein, the application of a mobile phase containing n-butanolacetic acid-water in volume composition 30:7:13, the use of silica gel 60F254 plates with concentrating zone, and subsequent application of 10% sulphuric acid in ethanol or 5% vanillin in methanol/sulphuric acid, respectively, provided the best results in a TLCdensitometric study of α-escin. The described method was successfully employed to identify α-escin in commercial samples that were in an oral dosage form (tablets) and also in the form of gel containing 20 mg of α-escin.

3

Biennial review of planar chromatography: 2011–2013

88%

Sherma J.

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issue 4

427-452

EN

The most important advances in planar chromatography published between November 1, 2011 and November 1, 2013 are reviewed in this paper. Included are an introduction to the current status of the field; student experiments, books, and reviews; theory and fundamental studies; apparatus and techniques for sample preparation and TLC separations (sample application and plate development with the mobile phase); detection and identification of separated zones (chemical and biological detection, TLC/mass spectrometry, and TLC coupled with other spectrometric methods); techniques and instruments for quantitative analysis; preparative layer chromatography; and thin layer radiochromatography. Numerous applications to a great number of compound types and sample matrices are presented in all sections of the review.

4

New N-aryloxy-phthalimide derivatives. Synthesis, physico-chemical properties, and QSPR studies

88%

Tudose M., Badea F., Caproiu M., Beteringhe A., Maganu M., Ionita P., Constantinescu T., Balaban A.

Open Chemistry

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2010

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vol. 8

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issue 4

789-796

EN

Starting from N-hydroxyphthalimide 1 and the reactive fluoro- or chloro-nitroaryl derivatives 2, 3 and 4a-e (2-chloro-3,5-dinitropyridine; 3, NBD-chloride; 4a, 1-fluoro-2,4-dinitrobenzene; 4b, picryl chloride; 4c, 4-chloro-3,5-dinitrobenzotrifluoride; 4d, 2-chloro-3,5- dinitrobenzotrifluoride; 4e, 4-chloro-3,5-dinitrobenzoic acid) the corresponding N-(2-nitroaryloxy)-phthalimide derivatives 5a-e, or 6 and 7 were obtained and characterized by IR, UV-Vis 1H-NMR and 13C-NMR spectroscopy. The TLC behavior and the hydrophobicity of these derivatives have been experimentally evaluated by RM0 parameters (using RP-TLC). The experimental RM0 parameters were compared with the calculated partition coefficient, log P. A QSPR study was also performed to establish possible correlations between the structure and physical properties (λmax and RM0) of compounds 5a-e, 6, and 7. [...]

5

Chemical characterization by TLC, UV, IR, HPLC-MS/MS and NMR of gossypetin-3’-O-glucoside from Talipariti elatum (Sw.) Malvaceae

75%

González J., Cuéllar A., Gaysinski M., Massi L., Monan M., Nossin E., François-Haugrin F.

World News of Natural Sciences

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2019

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vol. 24

100-116

EN

Talipariti elatum (Sw.) Malvaceae, also known as Blue Mahoe or Mountain Mahoe, commonly named as Majagua azul or Majagua, with red or crimson flowers, is a medicinal tree traditionally used against cough, asthma, catarrh, and expectorant. Its flowers contain a lot different chemical compounds, mainly flavonoids. From red petals of the flowers a flavonol glucoside was isolated and characterized by TLC, UV, IR, HPLC-MS/MS and NMR spectroscopy. Structure analyses of that chemical component revealed that It have the identical glucoside moiety attached to a flavonol skeleton like gossypitrin (gossypetin-7-O--glucoside) but in different position for which the structure of gossypetin-3’-O-glucoside was deduced from HSQC, HMBC, COSY and NOESY correlations.

6

Analysis of Organophosphorus Compounds. 1. Application of Iodine-Azide Reaction for Detection of Thiophosphoorganic Compounds in Thin-Layer Chromatography

63%

Kotyński A., Kudzin Z. H., Ciesielski W., Andrzej Kotyński - Department o f Bioinorganic Chemistry M. U. o. f. Ł., Zbigniew H. Kudzin - Institute of Chemistry U. o. Ł., Witold Ciesielski - Institute of Chemistry U. o. Ł.

Acta Universitatis Lodziensis. Folia Chimica

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2004

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vol. 13

PL