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Progressive course of isolated splenic myeloid sarcoma

100%

Antic D., Perunicic Jovanovic M., Knezevic D., Ostojic S., Elezovic I.

Open Medicine

2013

vol. 8

issue 4

499-502

A previously healthy 40-year-old male presented with a 2-week history of fever and abdominal discomfort that was resistant to empirical broad-spectrum antibiotic treatment. The patient’s blood cell count and complete biochemical panel was normal, except for an increased lactate dehydrogenase level. Ultrasonography and computed tomography of the abdomen showed a large, soft tissue mass had infiltrated superior part of the spleen. Splenectomy with total tumor mass removal were performed. The pathological examination of the tumor tissue confirmed diagnosis of isolated myeloid sarcoma with monoblastic differentiation. Despite intensive antileukemic therapy, patient died four months after diagnosis was established.

Carcinosarcoma of the spleen: literature review of a very rare tumour

61%

Rao A., Mathew G., Marimuthu K., Pandey U., Worlding J.

Open Medicine

2007

vol. 2

issue 2

230-235

Carcinosarcomas are rare tumours, which have both epithelial, and connective tissue elements. They are most commonly seen in the female genital tract. Rarely they arise from the gastrointestinal tract. We report a case of Carcinosarcoma arising as a primary in the spleen of a male aged 60yrs. The most unique feature of this tumour is the presence of osteosarcomatous element. This report highlights the importance of clinical awareness of such rare tumours and gives a brief overview on presentation, probable aetiology, diagnosis and management with literature review of carcinosarcoma.

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2 Open Medicine

1 2013

1 2007

1 Antic D.

1 Elezovic I.

1 Knezevic D.

1 Marimuthu K.

1 Mathew G.

1 Ostojic S.

1 Pandey U.

1 Perunicic Jovanovic M.

1 Rao A.

1 Worlding J.

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Progressive course of isolated splenic myeloid sarcoma

Carcinosarcoma of the spleen: literature review of a very rare tumour