The activity of rhodanese, 3-mercaptopyruvate sulfurtransferase and g-cystathionase and the content of glutathione and sulfane sulfur compounds were determined in Rana temporaria brain in April. The high sulfane sulfur level observed in the spring seems to be associated with protection against cellular oxidative stress after the period of hibernation with its minimal oxidative metabolism. Key words: sulfane sulfur, sulfurtransferases, glutathione, frog brain
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