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  1. 1 Biotechnologia

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  1. 1 1995

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  1. 1 Gorny A.

  2. 1 Mackiewicz A.

  3. 1 Wiznerowicz M.

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Gene therapy of cancer

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Gorny A., Wiznerowicz M., Mackiewicz A.
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Progress in genetic engineering has to lead to the development of efficient methods of transfer and expression of genes in eucariotic cells.This technology has been employed to kill cancer cells.Five major strategies of cancer gene therapy have been proposed and are currently verified in clinical trials.They include: (1) genetic cellular vaccines, (2) siuicide genes, (3) multidrug resistance genes, (4) HLA genes tansfer into cancer cells, and (5) repair of defective suppresor genes and/or removal of activated oncogene.
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