The term nutrigenomics refers to the effect of diet on gene expression, while the term nutrigenetics refers to the influence of genetic variation (single nucleotide polymorphisms and/or copy number variation) on the response to a specific diet, functional food or diet supplement. Nutrigenomics and nutrigenetics become an important new research areas because there is growing evidence that diet can influence the long-term risk for metabolic, degenerative or cancer diseases. Various nutrients can influence DNA and chromatine structure, regulation of transcription and signal transduction. Understanding of the diet-gene interactions will allow to redefine current concepts of preventive medicine or dietetics and improve functional food production.
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