Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl
Preferences help
Polish version English version Language
enabled [disable] Abstract
Number of results

Results found: 4

Number of results on page
first rewind previous Page / 1 next fast forward last

Search results

Search:
in the keywords:  LOCOMOTOR ACTIVITY
help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
1
Content available remote

Behavioural responsiveness to amphetamine or scopolamine following repeated exposure to chlorphenvinphos in rats

100%
Gralewicz S., Lutz P., Tomas T.
Acta Neurobiologiae Experimentalis
|
2002
|
vol. 62
|
issue 2
75-83
EN
A number of reports indicate that exposure to organophosphates (OPs), inhibitors of acetylcholinesterase (AChE), may result in long-lasting neurobehavioural alterations suggestive of an increased cholinergic tone. It is known that rats with cholinergic hyperreactivity are behaviourally hyposensitive to cholinergic antagonists and dopaminergic agonists.The purpose of the present study was to find out whether a similar trait would develop in rats exposed to chlorphenvinphos (CVP), an OP pesticide, in the past. The rats were given ten daily i.p. injections of CVP at doses of 0.5 mg/kg (group P-0.5) or 1.0 mg/kg (group P-1.0). The locomotion stimulating effect of i.p. injection of 1.0 mg/kg amphetamine (AMPH), or 0.7 mg/kg scopolamine (SCOP), was assessed on postexposure day 21 (group P-0.5) or 42 (group P-1.0), i.e. after a time sufficient for AChE recovery. The assessment revealed that in group P-1.0 the behavioural response to AMPH and SCOP was significantly depressed. In rats of the P-0.5 group, however, the behavioural response to each of the drugs was increased. The results suggest that, depending on the exposure level, contrasting alterations in some neurotransmitter systems may be induced by repeated exposure to CVP.
2
Content available remote

Bicuculline, AP-7 and behavioral activity in rats

100%
Car H., Kuziemka-Leska M., Wisniewski K.
Acta Neurobiologiae Experimentalis
|
1998
|
vol. 58
|
issue 2
159-164
EN
The effects of bicuculline (0.25 mg/kg i.p.) and AP-7 (5 nmols icv) on the processes of retrieval, consolidation of conditioned reflexes, object recognition and locomotor activity were tested in rats. Neither AP-7, nor bicuculline nor AP-7 with bicuculline changed locomotor and exploratory activity in the open field test. Coadministration of AP-7 with bicuculline however, facilitated retrieval of passive avoidance in rats, but was without effect on consolidation in this test. Also neither AP-7 nor bicuculline when were given alone had an effect on influenced consolidation. We found no differences in effects of either AP-7 or bicuculline on object recognition regardless whether administered alone or in combination.
3

The effect of dorsal raphe nucleus (DRN) lesions on the locomotor activity rhythm in mice

100%
Barbacka-Surowiak G., Gut M.
Folia Biologica
|
2001
|
vol. 49
|
issue 1-2
77-84
EN
The study employed electrical lesions of dorsal raphe nucleus (DRN) to determine the functional significance of those nuclei in the regulation of wheel-running activity rhythm in mice in light/dark (LD 12:12), constant light (LL), and constant dark (DD) conditions. The wheel-running records showed that raphe nucleus lesions resulted in few days? decrease in common activity and amplitude in LD. The activity phase was not compact but in fragmentary form, especially in DD condition. In some animals an earlier onset of activity after DRN lesion in LD was observed. In LL extension of the rhythm period occurred. Destruction of DRN only slightly modulates the wheel-running circadian rhythm in mice.
4
Content available remote

6-OHDA bilateral lesions to the central amygdala do not affect vasopressin improvement of recall in rats

100%
Winnicka M. M.
Acta Neurobiologiae Experimentalis
|
1996
|
vol. 56
|
issue 4
943-948
EN
The influence of vasopressin (AVP) on recall of information in a passive avoidance situation after bilateral 6-OHDA lesions to the central amygdala was tested. AVP given 15 min before the retention testing at the icv dose of 1 mg signifcantly prolonged avoidance latencies both in lesioned and in sham-operated rats in comparison with the respective icv saline injected animals. Insignificant increase of spontaneous locomotor activity in rats lesioned to the central amygdala was unlikely to interfere with the cognitive effect of AVP. These results suggest that dopaminergic projection to the central amygdala is not responsible for the facilitatory effect of AVP on retrieval process in a passive avoidance situation.
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.