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1

Macrophages, TGF-β1 expression and iron deposition in development of NASH

100%

Ananiev J., Penkova M., Tchernev G., Gulubova M.

Open Medicine

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2012

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vol. 7

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issue 5

599-603

EN

A wide range of molecular markers and different types of cells in liver are possible factors for progression of non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH) development of liver fibrosis. We investigated biopsies from 57 patients with NASH. The material was obtained from livers and was proceed immunohistochemistry antibodies against CD68 and TGF-beta 1. In addition, biopsies were evaluated for iron content. Macrophages/-positive/could be found in all 57 cases. The number of macrophages in the sinusoids correlated with the degree of portal fibrosis:64.% of the patients with mild or intensive fibrosis had high infiltration with CD68-positive cells, while 100% of the patients without fibrosis hadlow infiltration (χ2=8.56; p=0.003). In specimens we, 69.% of patients with different degree of fibrosis expressed TGF-β1 in their portal tracts, and 100% of patients without fibrosis did demonstrate expression of the protein (χ2=23.7; p<0.001). Hepatic iron was found in 100% (9) of patients with intensive fibrosis vs. 10.3% of the patients mild fibrosis (χ2=23.4; p<0.001). Our results suggest that the macrophages and macrophage-derived TGF-beta1 are the major factors responsible for development of fibrosis and progression of chronic liver disease.

2

Influence of Iron in AlSi10MgMn Alloy

100%

Žihalová M., Bolibruchová D.

Archives of Foundry Engineering

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2014

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issue 4

3

Iron-catalyzed hydrogenation and dehydrogenation reactions with relevance to reversible hydrogen storage applications

100%

Zell T., Langer R.

Recyclable Catalysis

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2015

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vol. 2

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issue 1

EN

Today’s energy concerns require the development of suitable solutions for the storage of energy from renewable resources. Although the chemical storage of energy using molecular hydrogen as energy carrier is one of the best options, this type of energy storage requires the conversion of hydrogen to liquid organic hydrogen careers (LOHCs) for practical reasons. This goal is challenging and highly desirable at the same time. In comparison to dihydrogen, hydrogen storage in LOHCs offers easier handling and minimum dangers involved in their production, storage, and reconversion. To achieve efficient processes based on LOHCs highly active catalyst systems are required which ideally are based on cheap and abundant metals such as iron. This review summarizes recent advances in ironcatalyzed hydrogenation and dehydrogenation reactions, with relevance to reversible hydrogen storage in small molecules. It entails the dehydrogenation reactions of formic acid and methanol water mixtures, the reverse reaction, the hydrogenation of CO2, dehydrogenation of alcohols, and the hydrogenation of different carbonyl compounds as the formal reverse reaction, as well as hydrogenation and dehydrogenation reactions of N-heterocyclic compounds and hydrogen release reactions from amino boranes.

4

Mechanical Characteristics of Ductile Iron Determined in an Original Modified Low Cycle test

100%

Maj M., Pietrzak K., Klasik A., Maj M., Pietrzak K., Klasik A.

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vol. 19

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issue 4

5

Combination of cloud point extraction and flame atomic absorption spectrometry for preconcentration and determination of trace iron in environmental and biological samples

88%

Ghaedi M., Shokrollahi A., Mehrnoosh R., Hossaini O., Soylak M.

Open Chemistry

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2008

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vol. 6

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issue 3

488-496

EN

In the presented work, the conditions for cloud point extraction of iron from aqueous solutions using 7-iodo-8-hydroxyquinolin-5-sulphonic acid (Ferron) was investigated and optimized. The procedure is based on the separation of its ferron complex into the micellar media by adding the surfactant Triton X-114. After phase separation, the surfactant-rich phase was dissolved with 1.0 M HNO3 in methanol. Iron was determined by flame atomic absorption spectrometry. Optimization of the pH, ligand and surfactant quantities, incubation time, temperature, viscosity, sample volume, and interfering ions were investigated. The effects of the matrix ions were also examined. The detection limits for three times the standard deviations of the blank for iron was 0.4 ng m L-1, enrichment factor of 19.6 and preconcentration factor of 30 could be achieved. The validity of cloud point extraction was checked by employing real samples including soil, blood, spinach, milk, meat, liver and orange juice samples using the standard addition method, which gave satisfactory results.In the presented work, the conditions for cloud point extraction of iron from aqueous solutions using 7-iodo-8-hydroxyquinolin-5-sulphonic acid (Ferron) was investigated and optimized. The procedure is based on the separation of its ferron complex into the micellar media by adding the surfactant Triton X-114. After phase separation, the surfactant-rich phase was dissolved with 1.0 M HNO3 in methanol. Iron was determined by flame atomic absorption spectrometry. Optimization of the pH, ligand and surfactant quantities, incubation time, temperature, viscosity, sample volume, and interfering ions were investigated. The effects of the matrix ions were also examined. The detection limits for three times the standard deviations of the blank for iron was 0.4 ng m L−1, enrichment factor of 19.6 and preconcentration factor of 30 could be achieved. The validity of cloud point extraction was checked by employing real samples including soil, blood, spinach, milk, meat, liver and orange juice samples using the standard addition method, which gave satisfactory results. [...]

6

Is adequate and balanced nutrition during pregnancy more effective than iron and folic acid supplements?

88%

Elmacioglu F., Surucu B., Alper T., Ozenoglu A., Ugurlu S.

Open Medicine

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2010

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vol. 5

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issue 2

235-242

EN

To provide instruction for pregnant women regarding adequate and balanced nutrition and determine whether iron and folic acid supplementation is essential. The research was an experimental clinical intervention. The study was conducted between March 2004 and May 2005 with 80 pregnant volunteers. The study participants were in their 16th to 24th weeks of pregnancy; all participants were healthy, carried only one fetus, and successfully completed their pregnancy. All participants were instructed about adequate and balanced nutrition. Until the participants gave birth, 40 (Group 1) consumed an iron-rich diet that was equivalent to the inclusion of a supplement containing 100 mg Ferro III plus 0,35 mg folic acid; the other group (Group 2) was also instructed in proper nutrition and was given by a gynecologist 1 tablet (100 mg) Ferro III hydroxide polymaltose complex and iron pharmaceutical with 0,35 mg folic acid (Maltofer Fol). In both groups, before and after the instruction, consumption frequency was noted, and the levels of serum ferritin, serum iron, total iron-binding capacity, folic acid, and vitamin B12 in the blood were determined at monthly intervals. Between the two groups, no statistical difference was found with regard to age, number of pregnancies, weight before pregnancy, body mass index (BMI) before pregnancy, and weight of the newborn (p>0,05). At the end of the study, the hemoglobin, hematocrit, and serum ferritin levels decreased considerably in both groups compared to the initial values (p<0.01). No statistically significant difference in serum ferritin levels could be found between the two groups (p>0,05). The comparison of Group I and Group II in terms of nutritional status (average energy and food consumption) in the pre-instruction and post-instruction periods revealed that intake of total protein, heme protein, dietary fiber, folic acid, carotene, vitamins A, B1, B2, B6, C, and B12, potassium, calcium, phosphorus, iron, and zinc was higher in Group I in the post-instruction period (p=0.000); no statistically significant change in nutritional status during pregnancy was observed in Group II. Conclusion: Medical diet programs with iron sources are examined in association with food consumption. Assessment of hematological results suggests that, during pregnancy, each patient should receive a specific dose, rather than a routine dose, of iron and folic acid.

7

Concentrations of retinol, α-tocopherol, copper, zinc and iron in plasma of young subjects differing in their engagement in motor activities

88%

Malara M., Hübner-Woźniak E., Kurczyńska A.

Biomedical Human Kinetics

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2012

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vol. 4

1-5

EN

Study aim: To assess possible effects of gender and of the level of motor activity on the deficiencies of selected vitamins and minerals in young subjects.Material and methods: Four groups of physical education (PE) students (n = 15 each) were studied: sedentary men (SM) and women (SF), and physically active men (AM) and women (AF) engaged in endurance sports, all aged 18 - 24 years, were studied. Somatic measurements included body height and mass, and body fat content (by Durnin's method, from 4 skinfolds), the biochemical ones included concentrations of retinol, α-tocopherol, copper, zinc and iron in plasma.Results: Men had significantly higher retinol (p<0.05) and iron (p<0.01) levels than women. The AM and SF groups had significantly (p<0.05 - 0.01) higher plasma levels of copper and zinc than Group SM. Group AF had lower zinc levels than Groups AM and SF, that latter group having lower α-tocopherol compared with Group SM.Conclusions: Inasmuch the observed differences could be due to the respective intakes, the effect of motor activity and the associated increased elimination of minerals could not be ruled out.

8

Isomers in the chemistry of iron coordination compounds

88%

Melnik M., Kohútová M.

Open Chemistry

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2010

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vol. 8

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issue 5

965-991

EN

The coordination chemistry of iron covers a wide field, as shown by a survey covering the crystallographic and structural data of almost one thousand and three hundred coordination complexes. About 6.7% of these complexes exist as isomers and are summarized in this review. Included are distortion (96.6%) and cis - trans (3.4%) isomers. These are discussed in terms of the coordination about the iron atom, bond length and interbond angles. Distortion isomers, differing only by degree of distortion in Fe-L, Fe-L-Fe and L-Fe-L parameters, are the most common. Iron is found in the oxidation states zero, +2 and +3 of which +3 is most common. The stereochemistry around iron centers are tetrahedral, five - coordinated (mostly trigonal - bipyramid) and six - coordinated. The most common ligands have O and N donor sites.

9

The Ti-Fe-P system: phase equilibria and crystal structure of phases

88%

Toma O., Dzevenko M., Oliynyk A., Lomnytska Y.

Open Chemistry

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2013

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vol. 11

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issue 9

1518-1526

EN

Abstract Phase equilibria was investigated in the Ti-Fe-P system at T = 1070 K in the region 0–67 at.% of P, employing X-ray powder diffraction. The two ternary compounds, namely Ti0.5–0.8Fe1.5−1.2P (Co2Si-type; space group Pnma; a = 0.5964(2)–0.6011(3), b = 0.3575(3)–0.3600(1), c = 0.6828(2)–0.6882(2) nm) and Ti0.85−1.25Fe1.15−0.75P (ZrNiAl-type; space group P-62m; a = 0.6071(4)–0.6117(1), c = 0.3510(9)–0.3506(1) nm) exist in the Ti-Fe-P system at this temperature. The crystal structure of the Ti0.85–1.25Fe1.15−0.75P compound was additionally determined by X-ray single crystal diffraction on the phase with stoichiometric composition. The substitutions of Ti by Fe were observed for Ti5P3.16, Ti3P and TiP phases, and Fe for Ti in the case of Fe3P, Fe2P binary compounds. Graphical abstract [...]

Refine search results

Macrophages, TGF-β1 expression and iron deposition in development of NASH

Influence of Iron in AlSi10MgMn Alloy

Iron-catalyzed hydrogenation and dehydrogenation reactions with relevance to reversible hydrogen storage applications

Mechanical Characteristics of Ductile Iron Determined in an Original Modified Low Cycle test

Combination of cloud point extraction and flame atomic absorption spectrometry for preconcentration and determination of trace iron in environmental and biological samples

Is adequate and balanced nutrition during pregnancy more effective than iron and folic acid supplements?

Concentrations of retinol, α-tocopherol, copper, zinc and iron in plasma of young subjects differing in their engagement in motor activities

Isomers in the chemistry of iron coordination compounds

The Ti-Fe-P system: phase equilibria and crystal structure of phases