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Systemic capillary leak syndrome due to systemic inflammatory response syndrome in infants: a report on 31 patients

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Yang C.-Y., Xu P., Yang Y.-J., Li B.-Y., Sun S.-Z., Yang Q.-Z., Wang L.-X.

Open Medicine

2014

vol. 9

issue 3

477-480

The aim of this study was to describe the clinical features, management strategies and outcomes of 31 infants with systemic capillary leak syndrome (SCLS) secondary to sepsis or systemic inflammatory response syndrome. There were 23 boys and 8 girls, with an average age 9.6 ± 2.1 days (range, 3.1 to 20 days). The primary disease was pneumonia in 11 patients and sepsis in other 20. Within 72 hrs of admission, all had progressive skin and mucosal edema, septic shock, respiratory distress, oliguria and severe hypoalbuminemia (10–20g/L). Other complications were pulmonary edema or hemorrhage, disseminated intravascular coagulopathy, heart failure, renal or liver dysfunction. All patients were treated with mechanical ventilation with a mean mechanical ventilation time of 19.7± 3.5 days. Intravenous hydroxyethyl starch was also applied at an early stage for 4–12 days, together with broad spectrum antibiotics, plasma and albumin infusion. Twenty one patients (67.0%) were discharged from the neonatal intensive care unit after a median stay of 29 days, and 7 died (37.0%) in the hospital. During a 6.3-month follow-up, 4 patients had hydrocephalus and another 4 had muscle spasm or rigidity in the lower-limbs. We conclude that SCLS is a serious complication of neonatal sepsis with a high rate of in-hospital mortality and post-discharge disability.

Change in movement patterns asymmetry in infants with central coordination disorder in continuous studies

100%

Urban K., Ignasiak Z., Wronecki K., Skrzek A.

Biomedical Human Kinetics

2015

vol. 7

issue 1

Study aim: the aim of the study was to observe the dynamics of changes in postural symmetry in infants during the first year of life, undergoing a therapy using the NDT-Bobath method. Material and methods: the study included a group of 60 term infants diagnosed with central coordination disorder. The course of psychomotor development in the children was compared with a control group of peers aged 3 and 12 months. Group I (study group) consisted of 40 infants who had been subjected to treatment using the NDT-Bobath method. Group II (control group) consisted of 20 infants who, by the decision of the parents, did not undergo the therapy. In group I, four studies were carried out at an interval of every 3 months ± 1 week. In group II, studies were carried out during the 3rd and 12th month. Results: symmetry in body position patterns and movement patterns were analysed. Three levels of a child’s body were subject to the assessment of symmetry. In each study disparities in movement patterns of the left and right side were assessed. Individual features were expressed using scores, according to the principle of the higher the score, the more intense asymmetry. Conclusions: 1. The observed changes in body postural asymmetry in infants during the first year of life are more favourable in the group of children undergoing rehabilitation. 2. The catch-up growth phenomenon among the infants from the control group proceeds more slowly and reaches beyond a child’s first year of life. This indicates the need to include appropriate methods of therapy.

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1 Biomedical Human Kinetics

1 Open Medicine

1 2015

1 2014

1 Ignasiak Z.

1 Li B.-Y.

1 Skrzek A.

1 Sun S.-Z.

1 Urban K.

1 Wang L.-X.

1 Wronecki K.

1 Xu P.

1 Yang C.-Y.

1 Yang Q.-Z.

1 Yang Y.-J.

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Systemic capillary leak syndrome due to systemic inflammatory response syndrome in infants: a report on 31 patients

Change in movement patterns asymmetry in infants with central coordination disorder in continuous studies