Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl

Refine search results

Journals help

  1. 2 Biotechnologia

Years help

  1. 1 2002

  2. 1 1997

Authors help

  1. 1 Cieslikowski T.

  2. 1 Kuczek K.

Preferences help
Polish version English version Language
enabled [disable] Abstract
Number of results

Results found: 2

Number of results on page
first rewind previous Page / 1 next fast forward last

Search results

Search:
in the keywords:  HETEROLOGOUS EXPRESSION
help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
1

New, engineered polyketide compounds synthesized by actinomycetes

100%
Kuczek K.
Biotechnologia
|
2002
|
issue 4
130-141
EN
Polyketides constitute a structurally and functionally diverse group of secondary metabolites produced by bacteria, fungi and plants. Macrocyclic polyketides are produced principally by actinomycetes using modular polyketide synthases which are giant multienzymes. These enzymes are potentially valuable for the biosynthesis of novel compounds. Engineered, hybrid polyketide synthases catalyse the formation of simple statin analogues, macrolactone ring analogues, and biologically active glycosylated compounds.
2

Heterologous genes expression in E. coli; interferon gamma as the model system

100%
Cieslikowski T.
Biotechnologia
|
1997
|
issue 2
71-92
EN
Interferon gamma is a molecule which may serve as a good object for studying and explaining the role of expression limiting conditions. Three levels of limiting factors modifications, i. e. operon choice and structure, changes in the secondary mRNA structure, and the influence of post-translational modulation processes are described. The relationship between the operon stucture and expression level for other heterologous proteins is compared with that of IFN-gamma. In particular, the shape of ribosome binding site (RBS) region and its affected different nucleotide substitutions are presented. The rule of N-terminal and C-terminal end changes for protein stability and inclusion body formation is also shown.
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.