Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl
Preferences help
Polish version English version Language
enabled [disable] Abstract
Number of results

Results found: 3

Number of results on page
first rewind previous Page / 1 next fast forward last

Search results

Search:
in the keywords:  HEPATITIS B VIRUS
help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
1

Clinical importance of PCR method for detection of hapatitis B virus DNA

100%
Sidorkiewicz M.
Biotechnologia
|
1996
|
issue 3
23-33
EN
Although a variety of hepatitis B marker are available to discriminate different states of hepatitis B virus (HBV) infection, there is a serious need to detect HBV DNA itself.For this reason, polymerase chain reaction (PCR), the most sensitive new technology, seems to be the best method.Indications for analysis of HBV DNA include early recognition of chronic hepatitis B, detection of HBV mutants, the study of interferon therapy results and many others.
2

Influence of genetic factors on the susceptibility to HBV infection, its clinical pictures, and responsiveness to HBV vaccination

80%
Kacprzak-Bergman I., Nowakowska B.
Archivum Immunologiae et Therapiae Experimentalis
|
2005
|
vol. 53
|
issue 2
139-142
EN
The association of genetic factors with hepatitis B virus (HBV) infection susceptibility, its different manifestations, and the different responses to hepatitis B antigen vaccination have been described by several authors. With regard to HLA class I molecules, association with HLA-B was especially observed. HLA-B35 and -B8 correlated with chronic active hepatitis (CAH) and with hepatitis B carriers. Correlation between HBV infection and HLA class II (loci DR and DQ) was also indicated, but results are not clear regarding the clinical pictures of the disease nor vaccination response. HLA class III (fourth complement component ? C4, third complement component ? C3, and properdin factor ? BF) are associated with various manifestations of this disease. The gammaglobulin phenotype Gm(1, 2, 3, 10, 21) was more frequent in CAH. However, in only three publications was the impact of HLA on the efficacy of interferon therapy taken into account.
3

Agrobacterium-mediated transformation of yellow lupin to generate callus tissue producing HBV surface antigen in a long-term culture

61%
Pniewski T., Kapusta J., Plucienniczak A.
Journal of Applied Genetics
|
2006
|
vol. 47
|
issue 4
309-318
EN
The idea of an oral vaccine administered as a portion of plant tissue requires a high level of antigen production. An improved protocol for the induction of transgenic yellow lupin calli or tumours, reaching 44% of transformation rate, is presented here. It has been developed by using the nptII marker gene and the uidA reporter gene as well as various Agrobacterium strains and plant explants. This method of seedling and hypocotyl transformation was applied to raise calli or tumours producing a small surface antigen of Hepatitis B Virus (S-HBsAg). Lupin tissue lines were long-term cultured on selection media maintaining the growth rate and high expression level of the native form of S-HBs, up to 6 mug per g of fresh tissue.
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.