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1

The protection of new developments in the field of Biotechnology by means of patent and plant varieties protection

100%
van Raden L.
Biotechnologia
|
1993
|
issue 4
40-45
2

The use of benthic algae, excluding diatoms and charales, for the assessment of the ecological status of running fresh waters: a case history from Germany

88%
Gutowski A., Foerster J., Schaumburg J.
|
2004
|
issue 2
3-15
EN
A biomonitoring program was developed to assess the ecological status of streams based on the phytobenthic algal community structure. The study presented here focuses on siliceous sites of streams in the central highlands of Germany. Phytobenthic algae belonging to eight classes and 74 taxa were grouped into four categories according to their ecological distribution pattern. A formula was designed to calculate an index ranging from +100 to ?100 to assess stream health. Based on these values, the sampling sites were assigned to one of the five ecological quality classes required by the Water Framework Directive (WFD) of the European Union.
3

High prevalence of the NBN gene mutation c.657-661del5 in Southeast Germany

88%
Maurer M., Hoffmann K., Sperling K., Varon R.
Journal of Applied Genetics
|
2010
|
vol. 51
|
issue 2
211-214
EN
Nijmegen breakage syndrome (NBS), a rare autosomal recessive chromosomal instability disorder, is caused by mutations in the NBN gene. Most patients known so far are of Slavic origin and carry the major founder mutation c.657-661del5. Due to an unexpectedly high incidence of NBS patients (homozygous for the c.657-661del5 mutation) in a Northeast Bavarian region in Southeast Germany, we estimated the prevalence of this mutation in this area and compared it to another German region. We found a high carrier frequency of 1/176 for the c.657-661del5 mutation among newborns in Northeast Bavaria, while the frequency of the mutation in Berlin was 1/990. We further studied families from a Slavic population isolate, the Sorbs, in the Lusatian region in Northeast Saxony, and revealed a prevalence of the c.657-661del5 mutation of 1/34. Whereas the Slavic origin of the Sorbs has been known, we attribute the surprisingly high frequencies of c.657-661del5 mutation in Bavaria (similar to frequencies of this mutation in various Eastern European countries) to a high percentage of people of Slavic origin in Northeast Bavaria.
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