Comparison of genome sequences has become an important approach to identify and understand biological significance of the variations and fluxes that occur through a genome. The main subject of the work concentrates on identification of indels and SNPs in large genomes and their potential application in biotechnology. Importantly, fine elaboration of genome structure and sequence polymorphism that results from resequencing promises to benefit breeding, biotechnology and medical research. The article also describes how the data extracted from comparative studies of genomes depends on phylogenetic distances of the species involved.
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