The major proteins from plasma and extracellular matrices (ECM) are described.The interaction of lymphoid cells with their microenvironment is critical for their growth and function.The interaction with ECM may play a significant role in defining the biological properties of many cells.ECM from a notework of bioactive proteins, that is being linked with an increasing number of processes, including antigen-independent activation, proliferation, homing and cell migration.Some aspects of the participation of the extracellular matrix in the language of intracellular communication is discussed.
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