Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl
Preferences help
Polish version English version Language
enabled [disable] Abstract
Number of results

Results found: 1

Number of results on page
first rewind previous Page / 1 next fast forward last

Search results

Search:
in the keywords:  CEREBELLAR DAMAGE
help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
1
Content available remote

Hypoxic damage of the cerebellum in 7-day-old rats. Ultrastructural and histochemical study

100%
Dambska M., Gajkowska B.
Acta Neurobiologiae Experimentalis
|
2002
|
vol. 62
|
issue 1
45-49
EN
The damaging influence of hypoxia on the cerebellum in immature rats, which is still discussed, was investigated. Using material obtained in a modified Levine model for combined hypoxic-ischemic damage in 7-day-old rats, we examined changes in cerebellum submitted to hypoxia only. The results demonstrated classic features of hypoxic nervous tissue damage and calcium accumulation in mitochondria and endoplasmic reticulum. This was investigated using electron microscopy combined with the oxalate-pyroantimonate method. We propose that Ca2+ increases in endoplasmic reticulum and mitochondrial Ca2+ pools may be involved in damage-mediated mechanisms. These results support a role of calcium as a mechanism of cerebellar cell loss after this form of injury.
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.