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Botulinum toxin: structure, mode of action and therapeutic use

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Tatarkiewicz J.
Postępy Higieny i Medycyny Doświadczalnej
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1994
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vol. 48
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issue 5
505-520
EN
Structure, biological activity, mode and mechanism of action botulinum toxin as well as its therapeutic use is described.Botulinum toxin type A, one of the most potent biologic toxins, has been found to be of therapeutic value in the treatment of several neurologic and opthalmologic diseases.Its ability to produce chemical denervation of muscles makes it option for treatment of disorders in which traditional therapeutic procedure are of limited value (e.g. blepharospasm and other focal dystonias, strabismus, spasticity).
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