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1

Potential accuracy of genetic evaluation for calving difficulty with incomplete data on calving difficulty and/or birth weight using a bivariate threshold-linear animal model

100%
Ramirez-Valverde R., Misztal M. I., Misztal I., Bertrand B. K., Bertrand K.
Journal of Applied Genetics
|
2001
|
vol. 42
|
issue 3
325-333
EN
The purpose of this study was to evaluate the potential loss of accuracy in direct and maternal predicted breeding values (PBV) for calving difficulty (CD) with different levels of missing records of CD and/or birth weight (BW), using a bivariate threshold-linear animal model. Data obtained from the American Gelbvieh Association included 84,420 first-parity records with both CD and BW available. The final pedigree file included 178,858 animals. The model included fixed calf-sex?dam-age, random herd-year-season, and animal direct and maternal effects. Different levels of missing observations for CD and BW were obtained by randomly deleting 0, 25, 50, 75, and 100% of records for both traits in various combinations. Correlation estimates between PBV for CD obtained with complete and incomplete data were used to measure the changes in PBV for different levels of missing records. Reported correlations are means of three replicates. The results suggest that the information on direct and maternal PBV provided by CD records is more reliable than the information provided by BW records. The difference was especially large when a high proportion of CD records were missing. Correlations above 0.96 and 0.95 for direct and maternal PBV, respectively, when missing 25% or 0% of the CD or BW records suggest that small changes would be predicted with a low proportion incomplete data. For genetic prediction of popular sires (with > 100 progeny), a higher proportion of missing records could be tolerated. The results suggest that the bivariate threshold-linear animal model is useful for routine genetic evaluation of CD with incomplete field data.
2

Association analysis of thyroglobulin gene variants with carcass and meat quality traits in beef cattle

100%
Gan G.-F., Zhang L.-P., Li J.-Y., Hou G.-Y., Li H.-D., Gao X., Ren H.-Y., Chen J.-B., Xu S.-Z.
Journal of Applied Genetics
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2008
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vol. 49
|
issue 3
251-255
EN
Thyroid hormones play an important role in regulating the metabolism and can affect the homeostasis of fat deposition. The gene encoding thyroglobulin (TG), producing the precursor for thyroid hormones, has been proposed as a positional and functional candidate gene for a QTL with an effect on fat deposition. In the present study, we identified 6 novel SNPs at the 3? flanking region of the TG gene. The SNP marker association analysis indicated that the SNP markers G133C, G156A, C220T and A506C were significantly associated with marbling score (P<0.05, N=271). Animals with the new homozygote genotype had higher marbling scores than those with the other genotypes. Besides, the linkage disequilibrium analysis indicated that these 4 SNPs were completely linked (r2 = 1). Results of this study suggest that the TG-gene-specific SNP may be a useful marker for meat quality traits in future marker-assisted selection programmes in beef cattle.
3

Cytognetic analysis of beef cattle

88%
Rejduch B., Slota E., Switonski M.
Genetica Polonica
|
1994
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vol. 35
|
issue 4
323-332
EN
A karyotpe analysis of 565 pedigree beef cattle was carried out as part of cytogenetic studies conducted at the Department of Immuno- and Cytogenetics of the National Research Institute of Animal Production.Using CBG-, GTG- and RBA- binding techniques, 16 cases of the 1;29 Robertsonian translocation were diagnosed in the Charolais breed (two bulls) and hybrids from the Blonde d' Aquitane bulls (4 bulls and 10 heifers).A homozygous form of translocation was identifiedin one heifer.A testicular biopsy and meiotic chromosome analysis were carried out in a bull-carrier of the 1;29 translocation .The presence of a trivalent, characteristic of a centric fusion, was observed.The population under study also showed XX/XY leucocytic chimerism in two young bulls.
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