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  1. 1 Biotechnologia

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  1. 1 1993

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  1. 1 Grajek W.

  2. 1 Lukaszynski D.

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Pilot plant and industrial systems for animal cell cultivation.I.Anchorage-dependent cell cultures

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Grajek W., Lukaszynski D.
Biotechnologia
|
1993
|
issue 2
8-21
EN
Several methods used to cultivate anchorage-dependent animal cells on a large scale are presented. These methods include the cultures on microcarriers in stirred and air-lift bioreactors, the cultures in hollow-fiber and flat-plate membrane bioreactors as well as the cultures attached to porous or fiber solid supports. The critical parameter in anchorage-dependent cultures is the adhesiveness of the cells to the carrier materials and the surface proliferation rate.
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