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Aspects of Applicability King - St. Clair Approximation in a Non-Newtonian Fluid Mechanics

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Włoch A., Czyż H., Jasiński T.
Acta Physica Polonica A
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2017
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vol. 132
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issue 1
164-166
EN
This studyis a contribution to research on the biomedical and clinical applications of ultrasound. Our research concerns the procedure for the separation of human blood fractions - erythrocytes. Ultrasonic waves can be used for the separation of cells in human blood. From a physical point of view, the human blood is a suspension of liquids and solids (cell elements), and behaves like a non-Newtonian fluid. Our work is devoted to the problem of the motion of red cells in human blood under the influence of ultrasonic wave. It defines a range of the applicability of approximation consisting in neglecting the nonlinear term in the friction force. It also analyzes the general properties of the equation of motion of the cell in the case of large attenuation constants, corresponding to the values of the drift forces for the cells with radii of a few μm. Finally, it defines the applicability criterion of the so-called King-St Clair approximation consisting in the assumption of equilibrium between the drift and the Stokes viscosity forces, neglecting the term representing inertia. This approximation permits analytical estimation of the time constants for the cell transport to points of stable equilibrium in an ultrasonic standing wave field.
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Ultrasonic Methods of the Cells Separation in Human Blood

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Włoch A., Czyż H., Jasiński T.
Acta Physica Polonica A
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2015
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vol. 128
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issue 2
234-236
EN
This work deals with the problem of ultrasound in the context of biomedical and clinical applications. Ultrasonic waves can be used for the separation of cells in human blood. Under the influence of ultrasonic waves cells included in the liquid experience a certain characteristic displacement was referred to as drift. Presented work suggests that only radiation pressure should be taken into account as a mechanism of drifting in this situation. It has been demonstrated that the growth of cells concentration around the points of stable equilibrium is exponential. The time constant of this growth was estimated and the formulae which determine the time needed to obtain the assumed concentration increase have been derived. The theoretical studies of acoustic agglomeration of particles in the liquid have become a new focus in the ultrasonic research.
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