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1;25 centric fusion recognition in the cattle chromosome by fluorescence in situ hybridization

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Ladon D., Solinas-Toldo S., Fries R., Stranzinger G.
Journal of Applied Genetics
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1996
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vol. 37
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issue 1
101-104
EN
Fluorescence in situ hybridization (FISH) experiments with specific probes for chromosome 29 and 25 were carried out on a Brown Swiss bull, previously diagnosed as a carrier of 1;29 centric fusion.The hybridization of the chromosome 29-specific probe (BMC 4216-already located on 29q13), produced signals on two small acrocentrics, but not the translocated chromosome.The signals appeared on the translocated chromosome and on a single chromosome 25 after hybridization of the chromosome-specific probe (BMC 3224 -previously located on 25q24).According to the actual nomenclature, the analysed aberration is a robertsonian translocation involving chromosomes 1 and 25.
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