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1
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Physical Recreation of Students of Selected Warsaw Non-Public Higher Education Institutions - Preferences and Motivations

100%
Dąbrowski A., Radiuk-Strzeżek J.
Physical Culture and Sport. Studies and Research
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2010
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vol. 48
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issue 1
99-109
EN
The creation of conditions within the teaching and educational system of higher education institutions that shape up rational, pro-health free-time behaviours is one of the key goals of the studies discussed in this paper. The starting point for every planned educational process is to investigate the present state of affairs, i.e. to perform a diagnosis. This paper presents the diagnosis results which indicate, based on the empirical research findings, the forms of leisure activities most often pursued and the motivations behind them. The method we used in our research was a diagnosis survey which covered 1,119 students.The dominant leisure-time activities preferred by the students we surveyed were watching TV and meeting friends. The third most popular student leisure activity was in the case of men spending time in front of a computer and in the case of the women walking. Nearly half of the female students and a little more than half of the male students practise their recreational activities outside the official school physical education classes. The men practise a little more often than the women. Football, cycling and swimming are the most popular sports among the men. The women prefer bicycle riding, gymnastic exercises, aerobics and volleyball. Both the male and female students gave as their first two most important motives for recreational physical activities their health and fitness aspects. The third motive varies, depending on sex. The female students appreciate rest and relaxation which they achieve through recreational physical activities. The men highlight the value of being in touch with nature. Although the students from the surveyed group say they do not engage in physical activity in their free time in any planned way, nearly 50% of them do so on a regular basis.
2
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Farmakoterapia krwawienia pochodzenia nieżylakowego z górnego odcinka przewodu pokarmowego

100%
Kurek K., Dąbrowski A.
Pediatria i Medycyna Rodzinna
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2013
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vol. 9
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issue 1
15-24
EN
Upper gastrointestinal bleeding is a common gastroenterological emergency requiring proper management and urgent treatment. The vast majority of these haemorrhages are due to peptic ulcers, erosive gastritis and esophagitis as well as oesophageal and gastric varices. Diagnostic and/or therapeutic endoscopy is recommended within 24 h of presentation in all patients with symptoms of upper gastrointestinal bleeding. Initial pharmacological treatment includes volume resuscitation, hemodynamic stabilization and proton pump inhibitor (PPI) (bolus 80 mg) administration prior to endoscopy to downstage the bleeding lesion. In patients on anticoagulants correction of coagulopathy is recommended prior to endoscopy. High-doses of PPI (8 mg/h for at least 3 days) administration after endoscopic haemostasis promote clot stability by sustaining intragastric pH above 6. H. pylori is the key factor in peptic ulcer development and eradication is recommended immediately after feeding is restarted. Presented management reduces rebleeding rate. Despite this upper gastrointestinal bleeding still carries considerable rates of complications and mortality. To aim of this work was to review the currently available guidelines and recommendations in pharmacological managing in patients with non-variceal upper gastrointestinal bleeding.
PL
Krwawienie z górnego odcinka przewodu pokarmowego jest powszechnym stanem nagłym w gastroenterologii, wymagającym szybkiego wdrożenia właściwego postępowania. Do najczęstszych przyczyn omawianej grupy krwawień zalicza się chorobę wrzodową, nadżerkowe zapalenie błony śluzowej żołądka i przełyku oraz żylaki żołądka i przełyku. U wszystkich chorych z objawami krwawienia z górnego odcinka przewodu pokarmowego zalecane jest wykonanie diagnostycznej i/lub terapeutycznej gastroskopii w ciągu 24 godzin od przyjęcia do szpitala. Początkowe leczenie farmakologiczne obejmuje resuscytację płynową, stabilizację hemodynamiczną chorego oraz podanie inhibitora pompy protonowej (proton pump inhibitors, PPI) (80 mg w bolusie) przed wykonaniem gastroskopii, co zmniejsza aktywność znamion krwawienia. Chorzy przyjmujący doustne antykoagulanty przed wykonaniem endoskopii wymagają ponadto wyrównania parametrów krzepnięcia. Stosowanie dużych dawek PPI (8 mg/godz. przez co najmniej 72 godziny) po uzyskaniu endoskopowej hemostazy warunkuje utrzymanie pH w żołądku powyżej 6, co umożliwia stabilizację skrzepu. H. pylori jest udokumentowanym czynnikiem ryzyka rozwoju wrzodów trawiennych, dlatego zaleca się przeprowadzenie terapii eradykacyjnej już w momencie wznowienia żywienia doustnego. Powyższe postępowanie obniża częstość nawrotu krwawienia nieżylakowego z górnego odcinka przewodu pokarmowego. Pomimo tego krwawienie z górnego odcinka przewodu pokarmowego ciągle obarczone jest znacznym ryzykiem powikłań i zgonu chorego. Celem niniejszej pracy był przegląd obecnie dostępnych zaleceń i wytycznych postępowania w krwawieniu z górnego odcinka przewodu pokarmowego pochodzenia nieżylakowego.
3
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Imaging of the Cervical and Abdominal Lymph Nodes in a Combined Treatment of Squamous Cell Oesophageal Carcinoma

81%
Ćwik G., Dąbrowski A., Skoczylas T., Wallner G.
Polish Journal of Surgery
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2011
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vol. 83
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issue 2
95-101
EN
The presence of lymph node metastases in esophageal cancer is one of the most principle prognostic indicators.The aim of the study was the assessment of cervical and abdominal lymph nodes (N/pN) by ultrasound (US) examination in patients with squamous cell carcinoma of the thoracic esophagus referred to esophagectomy.Material and methods. The analyzed study population consisted of 110 patients who underwent a combined-modality treatment (neoadjuvant chemotherapy - 74 patients or chemoradiotherapy - 36 patients). The results of US lymph node assessment were compared to the results of histopathological evaluation of lymph nodes harvested during surgery and diagnostic value of cervical and abdominal US in terms of sensitivity, specificity, positive and negative predictive value were determined.Results. The complete metastatic regression was shown by US in 14.3-22.2% of patients depending on the node location and mode of neoadjuwant treatment. There was no significant difference in the assessment of lymph nodes between chemotherapy and chemoradiotherapy patients.Conclusions. US investigation is a method recommended for the assessment of metastatic lymph nodes in squamous cell oesophageal carcinoma, especially - for cervical nodes, where its specificity amounted to 96% and sensitivity - 100%. When positive nodes are suggested by US of the neck esophagectomy should be combined with 3-field lymphadenectomy.
4
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The limits of weighing

81%
Jayaweeraa S. A. A., Robensb E., Dąbrowski A.
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2012
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vol. 67
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issue 1-2
31-43
EN
Mass determination in the gravitational field covers a wide measuring range and, as a comparative method, facilitates very sensitive measurements. However, gravity is a very weak force. First by application of acceleration fields and with mass spectrometric methods, the measuring range could be extended towards atomic and sub-atomic masses. There are only practical limits of weighing heavy masses. The mass of celestial objects can be determined by means of Kepler’s Laws.
5
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Practical Aproach to Variceal Gastrointestinal Bleeding – Association of Polish Surgeons Guidelines

72%
Wallner G., Solecki M., Dąbrowski A., Ćwik G., Dąbrowski A., Matyja A., Lampe P., Dziki A.
Polish Journal of Surgery
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2015
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vol. 86
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issue 5
248-256
6
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Stimulation of collagen biosynthesis by platelet homogenate in various cell cultures

70%
Bańkowski E., Dąbrowski A.
Acta Biochimica Polonica
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1980
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vol. 27
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issue 3-4
405-411
7
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Vascular Endothelial Growth Factor and Survivin Immunostaining in Gastric Adenocarcinoma

62%
Bury J., Szumiło J., Dąbrowski A., Ciechański A., Śliwińska J., Wallner G.
Polish Journal of Surgery
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2012
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vol. 84
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issue 7
341-347
EN
Two molecules - vascular endothelial growth factor involved in new vessels formation and survivin - antiapoptotic protein, reported to be associated with worse prognosis in various malignancies have been chosen for the study. Both are potential target for novel therapiesThe aim of the study was to determine the immunostaining of VEGF and survivin in gastric carcinoma and to analyse their relationship to the selected clinicopathological features and survival.Material and methods. Formalin-fixed, paraffin-embedded sections from 41 gastric adenocarcinomas were used for immunohistochemical reaction with monoclonal antibodies against vascular endothelial growth factor and survivin. The results were compared with selected clinicopathological features and survival.Results. Positive immunohistochemical reaction for vascular endothelial growth factor and survivin was revealed in 24 (58,53%) and 30 (73,17%), gastric carcinomas respectively. Vascular endothelial growth factor-negative gastric carcinomas were significantly more common in cases without metastases to regional lymph nodes and distant organs and in less advanced cases. Similar, distant metastases were also statistically less common in survivin-negative carcinomas. The differences in immunohistochemical reactions for survivin between less and more advanced cases almost reach statistical significance. The only factors significantly influenced 1, 2 and 3-year survival were vascular endothelial growth factor and survivin status. Statistically significant higher percentage of survival was noted in patients with vascular endothelial growth factor- and survivin-negative tumors.Conclusions. It seems that vascular endothelial growth factor and survivin play role in local invasion and spread of gastric adenocarcinoma and negatively influences survival. However, further studies are required to assess their true usefulness in the clinical practice.
8
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Evaluation of Endostatin and EGF Serum Levels in Patients with Gastric Cancer

62%
Masiak W., Szponar A., Chodorowska G., Dąbrowski A., Pedowski T., Wallner G.
Polish Journal of Surgery
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2011
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vol. 83
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issue 1
42-47
EN
The aim of the study was to assess angiogenesis markers - endostatin and endothelial growth factor (EGF) as markers of detection of gastric carcinoma.Material and methods. The study involved 20 patients with colorectal cancer (10 women, 10 men) aged 35 - 75 years, mean age = 55 years ± 11.2 who referred to the 2nd Department of General Surgery, Medical University in Lublin between June 2008 and June 2009. The control group comprised 10 volunteers (6 women, 4 men) who underwent upper gastrointestinal (GI) endoscopy due to the reflux disease and in whom gastric cancer was not diagnosed.Results. The mean endostatin concentration in controls was 5.21 ng/mL ± 1.37. Mean concentrations in patients with gastric cancer were higher than those in controls - 5.91 ng/mL ± 1.5. The difference was not statistically significant (p= 0.714). The EGF concentration in the control group was 28.19 pg/mL ± 12.94. EGF concentrations in patients with gastric cancer were higher compared to the control group - 28.8 pg/mL ± 12.63. The difference was not statistically significant (p= 0.85). The mean concentration of endostatin before the operation was 5.91 ng/mL ± 1.5 and after surgery was 5.33 ng/mL ± 2.01, the difference was not statistically significant.Conclusions. Blood endostatin and EGF quantitative determinations probably is not useful for detection of gastric carcinoma and effectiveness of treatment.
9
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Multichannel Intraluminal Impedance and pH Testing - A New Diagnostic Technique for Gastroesophageal Reflux Disease. Own Experience

62%
Wallner G., Solecki M., Huk J., Dąbrowski A., Majewski M., Dombroskyy A.
Polish Journal of Surgery
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2007
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vol. 79
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issue 7
490-495
EN
In 2001 FDA (Food and Drug administration, USA) gave its permission for simultaneous oesophageal intraluminal impedance examination and pH testing in the clinical practice. In 2002 in Porto, Portugal, a committee of international experts proposed a new classification of reflux types.Material and methods. From October 2005 to June 2006, we examined 36 patients sent to the clinic with GERD symptoms using a Sleuth® recording device.Results. The group of 36 patients (19 women and 17 men); mean age of 47 years with a range of 16-74 years) was examined. The mean length of time for the examination was 22 h 47 min, the shortest one lasting 18 h 36 min; brakes were caused by battery failure. 1509 episodes of reflux were confirmed by impedance channels. Only 538 (35.65%) of these reflux episodes were acidic or weakly acidic and 971 (64.35%) were non-acidic. There was one patient without acid reflux episodes during examination and only 12 non-acidic episodes. The proximal extend, defined as 15 cm above the LES, achieved 616 reflux episodes (40.82%). None of the patients had abnormal physical clearing times; 5 had extended chemical clearing times (13.8%) in recumbent positions.Summary. This paper is not a statistical evaluation of a MII-pH study and is only a report of our first experiences with this new diagnostic method. Objective evaluation of symptom correlation to reflux in MII and the chemical character of the refluxate gives a much more precise qualification to the best type of treatment. In cases of non-acidic reflux, MII-pH testing hastens decision making about surgery.
10
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The Impact of Nissen-Rossetti Fundoplication on the Perfusion in Microcirculation of the Gastric Fundus

62%
Przywara S., Wallner G., Dąbrowski A., Skoczylas T., Wroński J., Michalak K., Zymon R.
Polish Journal of Surgery
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2007
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vol. 79
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issue 9
581-586
EN
The aim of the study was to investigate the impact of Nissen-Rossetti fundoplication on the blood flow in the microcirculation of the gastric fundus.Material and methods. Eight patients undergoing Nissen-Rossetti fundoplication were included in the study. Perfusion in the gastric fundus was measured intraoperatively with laser Doppler flowmetry. An adhesive, flat, silicon probe was attached to the serosa in the same anatomical location during every measurement. Microcirculatory blood flow was recorded before and after fundoplication without ligation and division of the short gastric vessels.Results. In each patient, fundoplication led to increases in resting perfusion. Hyperperfusion was evoked by two mechanisms: increase in average blood flow and increase in vasomotion's amplitude and frequency.Conclusions. Fundoplication constitutes a new distribution of blood flow in the microcirculation of the gastric fundus, irrespective of its indication as a treatment of reflux disease or a supplement to cardiomyotomy in patients with achalasia. The procedure, when correctly performed, leads to local reactive hyperemia. Decreases in fundal perfusion suggest that the fundoplication wrap was created under excessive tension and may lead to dysphagia and local ischemia with consequences on motility of the lower esophagus. Thus, the assessment of change in perfusion of the gastric fundus after fundoplication might be a valuable tool in the routine quality control for appropriate performance of the fundoplication wrap.
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