Search results

Sort By:

Limit search:

Bile Infection and Bile Acids Concentration in Bile in Acute Biliary Pancreatitis

100%

Zasada J., Panek J., Dolecki M., Biesiada Z., Dembiński M.

issue 12

655-669

Biliary stones are the most common etiology of acute pancretitis (AP). Pathomechanism of this etiology is based on common channel theory of Opie.Material and methods. 113 patients with ABP were included in the study - 91 with mild and 22 with severe form of ABP. 17 patients with cholelithiasis and choledocholithiasis without ABP served as controls. All the patients were submitted to the same model of treatment. Endoscopic retrograde cholangiopancreatography (ERCP) with endoscopic sfincterotomy (ES) were performed in the day of admission and laparoscopic cholecystectomy within the next 24 hours. Bile specimens were taken from main bile duct (MBD) during ERCP and from gall-bladder (GB) during laparoscopic cholecystectomy. Bacteriological cultures, bile acids (BA) concentration and total and secretory form of IgA concentration were assessed in particular groups of patients.Results. No significant statistical differences of bile infection in MBD and GB were found between the analyzed groups of patients. Furthermore, the bile among the patients with severe ABP was more frequently infected, particularly when obtained from gall-bladder. Most common pathogens found in cultures were Gram negative bacteria. Interestingly, Gram positive cultures and fungi were also significant. The number of species of pathogens was of no significance for infection concerning both: source of bile and groups of patients. Mean concentrations of total BA were different between study groups of patients in MBD and in GB. It is worth mentioning, that the fraction of hydrophobic, secondary BA which are potentially more toxic, was increased in total concentration of BA in MBD particularly in patients with severe form of AP. Among patients with mild AP and controls these values were lower and similar.Conclusions. It seems that BA play as an aggressive factor during AP while in physiologic condition have a protective, antibacterial meaning.

STROKE FOLLOWING PERIPHERAL ARTERIO VENIUS MALFORMATION ALCOHOL EMBOLIZATION – SHOULD WE LOOK FOR PERSISTED FORAMEN OVALE IN ADVANCE?

86%

Błaż M., Ostrowska M., Zasada J., Maciąg R., Komar M., Michalski M., Trystuła M.

Acta Neuropsychologica

2022

vol. 20(1)

81-85

Stroke due to paradoxical embolism can be a complication of certain peripheral venous procedures in patients with coexisting patent foramen ovale. There is an established link between venous sclerotherapy and stroke, however there are no known reports of this complication following peripheral arteriovenous embolization.We present a case of a 36-year- old woman who experienced symptoms of disorientation and apraxia following a hypoxic event during percutaneous alcohol embolization of a large arteriovenous malformation in her right gluteal region. An MRI scan revealed multiple foci of restricted diffusion in both cerebral hemispheres corresponding to acute ischemic stroke lesions. As the subsequent work-up revealed patent foramen ovale, we speculate on the pathomechanism of stroke and conclude with a recommendation to screen for patent foramen ovale in patients undergoing peripheral venous procedures including arteriovenous malformation embolization.

Refine search results

1 Acta Neuropsychologica

1 Polish Journal of Surgery

1 2022

1 2009

2 Zasada J.

1 Biesiada Z.

1 Błaż M.

1 Dembiński M.

1 Dolecki M.

1 Komar M.

1 Maciąg R.

1 Michalski M.

1 Ostrowska M.

1 Panek J.

1 Trystuła M.

Search results

Bile Infection and Bile Acids Concentration in Bile in Acute Biliary Pancreatitis

STROKE FOLLOWING PERIPHERAL ARTERIO VENIUS MALFORMATION ALCOHOL EMBOLIZATION – SHOULD WE LOOK FOR PERSISTED FORAMEN OVALE IN ADVANCE?