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Treatment of multiple superficial basal cell carcinomas with topical imiquimod

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Brzeziński P., Chiriac A.
OncoReview
|
2015
|
vol. 5
|
issue 1
A42-A45
EN
Basal cell carcinoma is the most common malignancy of man. The use of the topical imiquimod 5% cream offers a noninvasive, nonsurgical, and an effective option for the treatment of primary types superficial basal cell carcinoma (sBCC). We present a case series of patients who used imiquimod 5% cream with good therapeutic effect. The medication had a good tolerability profile and there were no ocular adverse events. Imiquimod 5% cream could be considered the first choice treatment for BCCs in older patients who are poor candidates to surgery.
2
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Follicular mucinosis on the forehead of a 15-year-old girl

100%
Brzeziński P., Chiriac A.
OncoReview
|
2015
|
vol. 5
|
issue 3
A122-124
EN
Follicular mucinosis is a rare dermatosis characterized by accumulation of mucin in the follicular epithelium and sebaceous glands. Clinically, it is characterized by the presence of papules or well-circumscribed and infiltrative plaques. In this paper, we report a case of a 15-year-old girl, in which an asymptomatic, erythematous and infiltrative plaque evolved within a few weeks in the forehead region. There was no regression of the lesion with the use of topical glucocorticosteroids and isotretinoinum for 30 days.
3
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Skin of sailor: cutis rhomboidalis nuchae, actinic keratosis, squamous cell carcinoma and basal cell carcinoma. Case report

81%
Abdulaziz A., Brzeziński P., Chiriac A.
OncoReview
|
2014
|
vol. 4
|
issue 1
A37-41
EN
Chronic exposure to environmental ultraviolet radiation (UVR) plays a key role both in photocarcinogenesis and induction of accelerated skin ageing. Sailors commonly experience a significant number of cutaneous problems, related to the exposure to environmental factors due to their working conditions. Among these factors, sun exposure is able to determine both acute and chronic skin damage, mostly linked to the effects of the ultraviolet (UV) radiation on epidermal and dermal structures. We report a case of sailor with cutis rhomboidalis nuchae, solar elastosis, actinic keratosis (AK), numerous squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) of the head and trunk.
4
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Malignant melanoma of unknown primary site in patient with pustulosis plantaris

81%
Piotr B., Abdulaziz A., Andruszkiewicz J., Chiriac A.
OncoReview
|
2014
|
vol. 4
|
issue 2
A69-71
EN
We reported a 57 year old woman treated for 2 years because of pustulosis plantaris (periodic exacerbations and remissions). In July 2013 she reported to the Outpatient Surgery because of a tumor in the left groin area. The biopsy revealed: metastases melanomatosis in lymphonodus. The patients was in October at the surgical removal of lymph nodes from left groin area (lymphadenectomy groin - ilio - obturatorii right). Full diagnostic was carried out and searching of of primary foci to no results. In the patient revealed the presence of BRAF and she was qualified to study of drug vemurafenib.
5
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Primary cutaneous B-cell lymphoma located on the face and hard palate

61%
Brzeziński P., Chiriac A., Budurca R., Chiriac A. E., Pinteala T., Ivan L., Foia L.
OncoReview
|
2014
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vol. 4
|
issue 3
A113-116
EN
Introduction: Primary cutaneous B-cell lymphomas represent primary cutaneous lymphomas. The World Health Organization-European Organization for Research and Treatment of Cancer defines primary cutaneous B-cell limphomas as malignant lymphomas that are confined to the skin at presentation after complete staging procedures. Case report: We report a case of a woman with a cutaneous nodular B-cell lymphoma of the face, with very slow evolution that could easily be misdiagnosed. The patient had two non-ulcerated nodules on the left part of the face. A histological examination on both pieces following surgical excision showed a diffuse infiltrate of atypical B cells. The patient was subsequently directed to the Oncology Department for further investigation, but she died 24 hours afterwards due to one of the acute possible complications of the disease: pulmonary embolism. Conclusion: Cutaneous B-cell lymphoma is an unusual and rare skin neoplasm with a great range of clinical presentations and this is an alarm sign for apparent common skin lesion.
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