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A novel polypeptide from Cervus nippon Temminck proliferation of epidermal cells and NIH3T3 cell line

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Guan S.-W., Duan L.-X., Li Y.-Y., Wang B.-X., Zhou Q.-L.
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2006
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vol. 53
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issue 2
395-397
EN
A novel polypeptide, velvet antler polypeptide (VAPPs), having a stimulary effect on proliferation of some cell was isolated from the velvet antler of sika deer (Cervus nippon Temminck). This polypeptide consists of a single chain of 32 amino-acid residues VLSAT DKTNV LAAWG KVGGN APAFG AEALE RM. VAPPs showed marked stimulary effect on rat epidermal cells and NIH3T3 cell line (dose range from 10-40 mg·L-1 and 5-80 mg·L-1, respectively).
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