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Life with Oxidative Stress

100%
Gurda D., Kietrys A. M., Szopa A., Twardowski T.
Chemical and Process Engineering
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2012
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vol. 33
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issue 4
509-528
EN
Incomplete oxygen reduction gives rise to reactive oxygen species (ROS). For a long time they have been considered unwelcome companions of aerobic metabolism. Organisms using oxygen developed several systems of ROS scavenging with enzymatic and non enzymatic antioxidants, which allow them control the cellular level of oxygen derived from free radicals. It is well established nowadays that ROS are not necessarily negative byproducts, but they also play an important role in cellular mechanisms. They are involved in many regular cellular processes in all aerobic organisms. When the antioxidant system is overcome and the balance between ROS production and scavenging is disrupted, oxidative stress occurs. It has been reported that oxidative stress may be linked to some human diseases and is also involved in biotic and abiotic stress response in plants.
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A botanical and pharmacological description of petasites species

76%
Tys J., Szopa A., Lalak J., Chmielewska M., Serefko A., Poleszak E.
Current Issues in Pharmacy and Medical Sciences
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2015
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vol. 28
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issue 3
151-154
EN
The objective of this review was to evaluate the botanical and pharmacological description of Petasites species. Petasides (butterbur) as a perennial shrub which was found in Europe and also in a parts of Asia and North America, has been widely used medicinally for centuries. At present, the main phytopharmacology uses for Petasides extracts are for prophylactic treatment of migraines, as well as an antispasmodic agent for bronchial asthma and pertussis. Furthermore, it has been used effectively in preventing gastric ulcers, and in urinary tract spasms and treating patients with irritable bladder. But still, there is a need for more studies on the potential applications of butterbur extract in medicine.
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