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Is consumption of vegetables and fruit a protective factor against kidney cancer?

100%

Azeem K., Tomášková H., Horáková D., Magnusková S., Ševčíková J., Janout V., Kollárová H.

Open Medicine

2013

vol. 8

issue 3

364-368

The role of vegetable and fruit consumption in the aetiology of kidney cancer was analyzed using data from a case-control study conducted in two centres in the Czech Republic between 1999 and 2003. The study comprised 300 patients with newly diagnosed, histologically confirmed kidney cancer and 335 controls. Information on dietary habits was obtained using a standardized food frequency questionnaire including 23 food items. Odds ratios (ORs) and 95% confidence intervals were calculated using logistic regression models. A strong protective effect of vegetables consumption on renal cell carcinoma risk was observed among people with high consumption of fresh vegetables (OR 0.42 95% CI (0.29–0.60)) and cooked vegetables (OR 0.71, 95% CI (0.51–1.00)). The protective role of fresh fruit was significant as crude OR 0.71, 95% CI (0.50–1.00), but after adjusting for the main risk factors no association was found (OR 1.08, 95% CI (0.71–1.64)). The protective role of pickled vegetables disappeared after adjustment for the main risk factors.

The role of selected risk factors for development of oesophageal cancer

84%

Kollárová H., Azeem K., Magnusková S., Tomášková H., Ševčíková J., Horáková D., Kamarád V., Janout V.

Open Medicine

2013

vol. 8

issue 1

30-40

A hospital-based analytical observational case-control study of 88 oesophageal cancer cases and 200 controls was conducted in the University Hospital Olomouc. A standardized questionnaire was used. The adjusted odds ratio (OR) are calculated by logistic regression. The adjusted odds ratios for tobacco smoking were 6.20 (95% CI 2.78–13.83), 10.64 (95% CI 3.46–32.72) and 3.53 (95% CI 1.26–9.88) for oesophageal cancer, for oesophageal squamous cell carcinoma, and oesophageal adenocarcinoma, respectively. An inverse association with overweight and obesity was found in both histological types. In adenocarcinoma, there was a relatively strong positive association with a statistically significant result for alcohol consumption only in a group consuming more than 300 g of alcohol weekly; the OR was 5.81 (95% CI 1.17–28.84). The strong, statistically significant association was found in alcohol consumption regardless of histological type: the OR was 4.41 (95% CI 1.09–17.84). In a group with 20 or more X-ray exposures, there was a very strong statistically significant positive association. In vegetable consumption, an inverse association was found that was statistically significant only if more than 8 portions of vegetables were eaten weekly, ORs were 0.02–0.11.

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2 Open Medicine

2 2013

2 Azeem K.

2 Horáková D.

2 Janout V.

2 Kollárová H.

2 Magnusková S.

2 Tomášková H.

2 Ševčíková J.

1 Kamarád V.

Search results

Is consumption of vegetables and fruit a protective factor against kidney cancer?

The role of selected risk factors for development of oesophageal cancer