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Various functions of human erythrocyte membrane lipids

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Bucki R., Sulpice J.-C., Giraud F., Gorski J.
Postępy Higieny i Medycyny Doświadczalnej
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1997
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vol. 51
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issue 6
637-650
EN
The major phospholipid classes of the human red blood cell membrane are: phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine and sphingomyeli. These phospholipids are distributed asymmetrically across the two halves of the lipid bilayer. this asymmetry appears to be generated and maintained by an ATP-dependent translocation of aminophospholipids from outer to inner leaflet, and by the interaction of phospholipids with skeletal proteins. The phosphoinositides account for 3-4% of total erythrocyte membrane phospholipid. They play an important role in signal transduction and are involved in other various membrane functions.
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