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1
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Investigation of Phonons in HgCdMnTe Using Far-Infrared Reflectivity

100%
Dudziak E., Bożym J., Pruchnik D., Baran J.
Acta Physica Polonica A
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1993
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vol. 84
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issue 3
595-598
EN
The first reflectivity spectra of Hg_{1-x-y}Cd_{x}Mn_{y}Te with 0.03 < x < 0.1 and 0 < y < 0.05 were measured in the spectral region 700-30 cm^{-1} at 300 K and 90 K. The quaternary alloys measured show three mode behaviour. The experimental results are interpreted by using a classical dynamic dielectric function model.
2
Content available remote

Specific Heat of (NH_{2}(CH_{3})_{2})_{3}Bi_{2}I_{9}

88%
Plackowski T., Włosewicz D., Tomaszewski P., Baran J., Marchewka M.
Acta Physica Polonica A
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1995
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vol. 87
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issue 3
635-641
EN
The specific heat of title compound was measured by adiabatic calorime­ter in the temperature range 80-315 K. The phase transitions at about 304, 285 and 235 K were confirmed. A new structural phase transition at about 125 K was observed as well as new anomaly on differential scanning calorimetry (DSC) curve at about 318 K. The peculiar multiple character of C, anomalies may be explained in terms of phase transitions or intermediate phases induced by impurities. The specific heat data are in agreement with the independent DSC measurements and with preliminary X-ray studies.
3

Induction of DNA breakage in U937 cells by oxazaphosphorines

88%
Mazur L., Opydo-Chanek M., Stojak M., Baran J., Niemeyer U.
Folia Biologica
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2010
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vol. 58
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issue 1-2
15-20
EN
Oxazaphosphorines are a class of DNA alkylating agents. The aim of the present study was to compare the possible influence of three new generation oxazaphosphorines, D-17272 (mafosfamide cyclohexylamine salt), D-18864 (4-hydro-peroxy-cyclophosphamide), and D-19575 (glufosfamide, beta-D-glucose-isophosphoramide mustard) on DNA damage induction in the human histiocytic lymphoma U937 cells. The flow cytometry APO-BRDUTM assay, based on the TUNEL method, was used for the in situ detection of DNA strand breaks. After exposure of U937 cells to the oxazaphosphorines, the patterns of temporary changes in the frequency of TUNEL positive U937 cells, expressing DNA breakage, were determined. The effects of the oxazaphosphorines on U937 cells were dependent on the agent tested and its dose, and the time intervals after the drug application. The different potential of D-17272, D-18864 and D-19575 to induce DNA strand breakage in the human histiocytic lymphoma U937 cells was shown.
4
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Dielectric Dispersion in Ferroelectric Glycine Phosphite

76%
Tchukvinskyi R., Czapla Z., Sobiestianskas R., Brilingas A., Grigas J., Baran J.
Acta Physica Polonica A
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1997
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vol. 92
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issue 6
1191-1196
EN
Dielectric dispersion in ferroelectric hydrogen bonded glicyne phosphite crystal was investigated in the frequency range 100 Hz - 27 GHz. Dielectric relaxation of Debye type observed in the paraelectric phase shows a critical slowing down of the polarization fluctuations. The relaxation frequency decreases with temperature according to f_{s} = 0.305(T-T_{0}) GHz in the paraelectric phase. The activation energy for flipping dipole motion ΔU = 2.07kT_{c} confirms order-disorder character of the phase transition. In the ferroelectric phase pronounced low frequency (100 Hz - 1 MHz) dispersion related to domain contribution to permittivity was found.
5

The migration of bone marrow-derived non-hematopoietic tissue-committed stem cells is regulated in an SDF-1-, HGF-, and LIF-dependent manner

64%
Kucia M., Wojakowski W., Reca R., Machalinski B., Gozdzik J., Majka M., Baran J., Ratajczak J., Ratajczak M. Z.
Archivum Immunologiae et Therapiae Experimentalis
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2006
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vol. 54
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issue 2
121-135
EN
Introduction: Recently we identified in bone marrow (BM) by employing chemotactic isolation to SDF-1 gradient combined with real time RT-PCR analysis a mobile population of CXCR4+ BM mononuclear cells that express mRNA for various markers of early tissue-committed stem cells (TCSCs). In this study we evaluated whether TCSCs respond to other moto-morphogens, such as hepatocyte growth factor (HGF) and leukemia inhibitory factor (LIF). Materials and Methods: We again employed chemotactic isolation combined with real-time RT-PCR analysis to assess whether murine and human BM contain TCSCs that respond to HGF and LIF gradients. We also evaluated expressions of HGF and LIF in damaged organs. Results: We noted that the number of TCSCs is highest in BM from young (1- to 2-month-old) mice and decreases in 1-year-old animals. Murine and human TCSCs 1) respond to HGF and LIF gradients in addition to an SDF-1 gradient, 2) reside in populations of BM-derived non-hematopoietic CD45? cells, and 3) are released (mobilized) from BM into the peripheral blood (PB) during tissue injury (e.g. after partial body irradiation). Conclusions: These findings further support our theory of the BM as a ?hideout' for TCSCs and we suggest that their presence in BM tissue should be considered before experimental evidence is interpreted simply as transdifferentiation/plasticity of hematopoietic stem cells. Since we demonstrated that not only SDF-1, but also HGF and LIF are upregulated in damaged tissues, we postulate that CXCR4+ c-Met+ LIF-R+ TCSC could be mobilized from the BM into the PB, from which they are subsequently chemoattracted to damaged organs, where they play a role in tissue repair/regeneration.
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