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1
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Schwannoma nerwu twarzowego w odcinku pozaczaszkowym – opis przypadku

100%
Tarazewicz D., Wierzchowska M., Burduk P.
Polski Przegląd Otorynolaryngologiczny
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2019
|
vol. 8(3)
45-49
PL
Schwannoma (nerwiaki osłonkowe) to łagodne, dobrze odgraniczone guzy powstające z komórek Schwanna, tworzących osłonki mielinowe nerwów obwodowych, czaszkowych lub korzeni nerwów rdzeniowych. 25–45% z nich lokalizuje się w obrębie głowy i szyi, głównie w przestrzeni przygardłowej. Lokalizacja wewnątrzprzyusznicza jest rzadko spotykana. Etiologia nowotworu nie jest znana. Diagnostyka przedoperacyjna zarówno radiologiczna, jak i cytologiczna jest trudna i często nie daje prawidłowego rozpoznania. Radiologicznie zwykle podejrzewany jest gruczolak wielopostaciowy, a materiał z biopsji cienkoigłowej nie jest diagnostyczny. Leczenie z wyboru to chirurgiczne usunięcie zmiany z próbą zachowania funkcji nerwu twarzowego.
2
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Trudności diagnostyczne w rozpoznaniu COVID-19 u pacjenta po laryngektomii całkowitej

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Czech J., Burduk P., Wierzchowska M.
Polski Przegląd Otorynolaryngologiczny
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2021
|
vol. 10(2)
44-47
PL
Choroba COVID-19 wywoływana jest przez wirusa SARS-CoV-2 i często manifestuje się objawami grypopodobnymi, które mogą przebiegać z różnym nasileniem. W dalszej kolejności może prowadzić do ostrej niewydolności oddechowej (ARDS). Podstawowe testy diagnostyczne identyfikują materiał genetyczny wirusa w próbkach wydzielin z dróg oddechowych. Chorzy po laryngektomii całkowitej z uwagi na zmieniony przebieg dróg oddechowych wymagają szczególnej uwagi pod względem diagnostyki w kierunku zakażenia SARS-CoV-2. W naszej pracy przedstawiamy przypadek pacjenta po laryngektomii, u którego uzyskano różne wyniki testów w kierunku COVID-19 w zależności od miejsca pobrania próbek. Słowa kluczowe: SARS-CoV-2, laryngektomia, drogi oddechowe
3
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Chirurgiczna rehabilitacja głosu chorych po laryngektomii całkowitej z zastosowaniem systemu Provox

100%
Bilewicz R., Burduk P. K., Kopczyński A., Wierzchowska M.
Otolaryngologia Polska
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2007
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vol. 61(3)
265-270
PL
The aim of study. Comparison the voice quality of patients after total laryngectomy using the Provox 2 voice prosthesis and patients with esophageal speech and to discuss difficulties and complications related with its implantation. Material and methods. The study group consists of 39 patients after total laryngectomy and Provox puncture. 36 patients underwent primary puncture, 3 patients – secondary puncture. 32 patients underwent radiotherapy. The time starting of speech learning was approx the 9th day after total laryngectomy and 1st-3th day after secondary implantation. The authors subjectively and objectively analyzed voice of 34 patients with fistular speech and it compared with esophageal speech of 10. The spectrograms analysis of the voice was based on Remacle’s scale. The study showed juxtaposition of early and late complications of patients with voice prostheses. Results. 90% of patients (35 patients) learned the fistular speech. The speech was louder and more intelligible than esophageal voice in subjective estimation. The fistular voice had higher of mean volume (61,1 dB vs. 59 dB), mean longer maximum phonation time (9,5 s vs. 2,2 s), mean higher base frequency F0 (108 Hz vs. 87Hz) and smaller variability of F0 based on mean Jitter ratio (3,8% vs. 6,6%), mean Shimmer ratio (23,18% vs. 23,52%) and mean HPQ ratio (127,34 vs. 141,73) than esophageal voice in objective estimation. Mean range of frequency of the speech was smaller but it was in higher frequencies. The most frequent type of spectrogram was 3th type in experimental group and 2nd type in control group. The mean lifetime of prostheses was 295 days. The most common cause of replacement of the prosthesis was leakage associated with mycosis infection (26 cases). Early complications were observed. The most frequent of them was infection around the fistula during supplementary radiotherapy (7 cases after primary puncture). The most frequent of later complications was widening of fistula and leakage around prosthesis (4 cases). Conclusions. Rehabilitation of patients after total laryngectomy is better using Provox system than learning esophageal speech (according to voice quality aspect). Using of voice prostheses in patients after total laryngectomy can combine with appearance of complications.
4
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The surgery voice rehabilitation after total laryngectomy with the Provox system

100%
Bilewicz R., Burduk P. K., Kopczyński A., Wierzchowska M.
|
EN
The aim of study. Comparison the voice quality of patients after total laryngectomy using the Provox 2 voice prosthesis and patients with esophageal speech and to discuss difficulties and complications related with its implantation. Material and methods. The study group consists of 39 patients after total laryngectomy and Provox puncture. 36 patients underwent primary puncture, 3 patients – secondary puncture. 32 patients underwent radiotherapy. The time starting of speech learning was approx the 9th day after total laryngectomy and 1st-3th day after secondary implantation. The authors subjectively and objectively analyzed voice of 34 patients with fistular speech and it compared with esophageal speech of 10. The spectrograms analysis of the voice was based on Remacle’s scale. The study showed juxtaposition of early and late complications of patients with voice prostheses. Results. 90% of patients (35 patients) learned the fistular speech. The speech was louder and more intelligible than esophageal voice in subjective estimation. The fistular voice had higher of mean volume (61,1 dB vs. 59 dB), mean longer maximum phonation time (9,5 s vs. 2,2 s), mean higher base frequency F0 (108 Hz vs. 87Hz) and smaller variability of F0 based on mean Jitter ratio (3,8% vs. 6,6%), mean Shimmer ratio (23,18% vs. 23,52%) and mean HPQ ratio (127,34 vs. 141,73) than esophageal voice in objective estimation. Mean range of frequency of the speech was smaller but it was in higher frequencies. The most frequent type of spectrogram was 3th type in experimental group and 2nd type in control group. The mean lifetime of prostheses was 295 days. The most common cause of replacement of the prosthesis was leakage associated with mycosis infection (26 cases). Early complications were observed. The most frequent of them was infection around the fistula during supplementary radiotherapy (7 cases after primary puncture). The most frequent of later complications was widening of fistula and leakage around prosthesis (4 cases). Conclusions. Rehabilitation of patients after total laryngectomy is better using Provox system than learning esophageal speech (according to voice quality aspect). Using of voice prostheses in patients after total laryngectomy can combine with appearance of complications.
5
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Diagnostic difficulties with COVID-19 in a patient after total laryngectomy

100%
Czech J., Burduk P., Wierzchowska M.
Polski Przegląd Otorynolaryngologiczny
|
2021
|
vol. 10(2)
44-47
EN
Coronavirus disease (COVID-19) is caused by the SARS-CoV-2 virus and often presents with flu-like symptoms that can have varying degrees, which may subsequently lead to acute respiratory distress (ARDS). The genetic material of the virus in samples of respiratory secretions is identified by way of basic diagnostic tests. Due to the altered course of the respiratory tract, patients after total laryngectomy require special attention in the diagnosis of SARS-CoV-2 infection. We present a case of a patient after laryngectomy who obtained different results of COVID-19 tests depending on the site of sampling.
6
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A schwannoma of facial nerve in the extracranial segment – a case report

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Tarazewicz D., Wierzchowska M., Burduk P.
Polski Przegląd Otorynolaryngologiczny
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2019
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vol. 8(3)
44-49
EN
The report aims to present a rare case of facial nerve schwannoma within the parotid gland. Schwannomas are benign, welldefined tumours arising from Schwann cells that form the myelin sheaths of peripheral, cranial or spinal nerves. 25–45% of them are located within the head and neck, mainly in the parapharyngeal space. The intraparotid localisation is rare. The aetiology of cancer is unknown. Preoperative diagnosis, both radiological and cytological, is difficult and often does not give the correct diagnosis. Radiologically, a multiform adenoma is usually suspected, and fine needle aspiration biopsy is nondiagnostic. Due to the rarity and benign nature of the tumour, there has been debate over the need for surgical treatment.
7
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Tissue remodelling in chronic rhinosinusitis – review of literature

76%
Radajewski K., Wierzchowska M., Grzanka D., Antosik P., Zdrenka M., Burduk P.
Otolaryngologia Polska
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2019
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vol. 73(5)
1-4
EN
CRS is a process involving a number of adverse changes in the mucosa of the paranasal sinuses and nasal polyps, e.g. increased fibroblast proliferation, angiogenesis, increased formation of fibrous tissue (subepithelial fibrosis) and tissue destruction. There are biomarkers whose levels can be increased in chronic inflammation of the paranasal sinuses: peripheral blood eosinophilia, IgE immunoglobulin, cytokines – IL-4, IL-5, IL-13, IL-25, IL-33, periostin, P-glycoprotein, CXCL-12, CXCL-13, INF-Υ, TNFα, TGFβ1, albumins, eotaxin. These biomarkers are not pathognomonic for CRS. The concentration of biomarkers is also increased in bronchial asthma and atopic dermatitis. The TGFβ, in particular the β1 subunit, was identified as the main factor involved in the remodelling of tissue stroma. In conjunction with continuous improvement of tissue testing methods, it is advisable to search for new factors that will more accurately allow the assessment of tissue remodelling in the chronic processes of paranasal sinuses.
8
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Remodeling tkankowy w przewlekłym zapaleniu zatok przynosowych – przegląd piśmiennictwa

76%
Radajewski K., Wierzchowska M., Grzanka D., Antosik P., Zdrenka M., Burduk P.
Otolaryngologia Polska
|
2019
|
vol. 73(5)
1-4
PL
Remodeling tkankowy w przewlekłym zapaleniu zatok przynosowych (CRS – chronic rhinosinusitis) to proces obejmujący szereg niekorzystnych zmian w śluzówce zatok przynosowych oraz polipach nosa, m.in.: zwiększoną proliferację fibroblastów, angiogenezę, zwiększone tworzenie tkanki włóknistej (włóknienie podnabłonkowe) oraz degenerację tkanek. Wykazano biomarkery, których stężenie może być zwiększone w przewlekłym stanie zapalnym zatok przynosowych: eozynofilię krwi obwodowej, immunoglobulinę IgE, cytokiny – IL-4, IL-5, IL-13, IL-25, IL-33, periostinę, glikoprotenę-P, CXCL-12, CXCL-13, INF-ϒ, TNFα, TGFβ1, zawartość albumin, eotaksynę. Wymienione biomarkery nie są jednak patognomoniczne dla tej jednostki chorobowej. Ich stężenie wzrasta również w astmie oskrzelowej oraz atopowym zapaleniu skóry. Jako główny czynnik, biorący udział w przebudowie podścieliska tkanek, określono transformujący czynnik wzrostu beta (TGFβ), w szczególności podjednostkę β1. Ze względu na nieustanne doskonalenie metod badań tkanek, wskazane jest poszukiwanie nowych czynników, które w sposób bardziej dokładny umożliwią ocenę przebudowy tkankowej w procesach chorobowych zatok przynosowych.
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