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Evolution of the Mechanical Suture

100%
Klimczak A., Mirosławska-Kempińska B., Mik M., Dziki A.
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vol. 85
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issue 1
44-46
2
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Resections and Palliative Procedures in Patients Operated on for Colorectal Cancer in Poland in 2005-2008

88%
Klimczak A., Mik M., Dziki Ł., Seroka W., Dziki A.
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2010
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vol. 82
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issue 11
621-625
EN
The aim of the study was analysis of the number of resection and palliative procedures in patients operated on for colorectal cancer in Poland. We also analyzed the number of sphincter-sparing surgery in patients with rectal cancer.Material and methods. Statistical data about surgical procedures performed in patients with colorectal cancer were obtained from the National Institute of Hygiene in Warsaw. The procedures were divided into palliations and resections. The analysis was performed for the period from 2005 to 2008. We analyzed the data including women and men.Results. We observed an increase in the number of resections from 3381 to 3768 (85.6-88% of all treatments) (2005-2008) in patients with colon cancer. A similar regularity was observed in patients who underwent surgery for rectal cancer from 2335 to 2712, respectively (76.4 to 81.4% of all treatments). Similarly, the number of sphincter-sparing surgery over the course of the period has increased from 1502 to 1916 operations.Conclusions. The increase in the percentage of resections and sphincter-sparing surgery may indicate the progress in the earlier detection of colorectal cancer. Another reason for this increase may be improving the level of education of surgeons due to the better availability of workshops and training. However, analysis is based on too short period of time and these conclusions cannot be regarded as final.
3
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Manual Stitching - the Past and the Present

88%
Klimczak A., Mirosławska-Kempińska B., Biegańska-Płonka M., Mik M., Dziki A.
Polish Journal of Surgery
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2011
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vol. 83
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issue 9
527-530
4
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Rola kwasu hialuronowego w wybranych jednostkach chorobowych

52%
Malinowska K., Klimczak A., Możdżan M., Modranka R., Śmigiel K., Piątkowski P., Merecz-Sadowska A., Skowerski Ł., Zajdel R., Levadna T., Zielińska-Bliźniewska H., Tomaszewski W.
Polish Journal of Sports Medicine
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2018
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vol. 34(4)
197-212
EN
Hyaluronic acid (HA) is a polysaccharide (glycosaminoglycan), which is normally present in all living organisms. Its chemical constitution is identical in mammals and bacteria. This mucopolisaccharide chain may consist of even several thousands of saccharide subunits. The unique, highly elastic nature of HA, together with its bio-compatibility and the lack of immunogenic potential in relation to the human body, have contributed to the widespread use of this substance in many clinical solutions including supplementation of the synovial fluid in patients with joint inflammation as an adjuvant agent in ophthalmic and dental surgery and the preparation accelerating postoperative wound healing. Recent studies assess the properties of HA, a potential drug carrier in various applications including eye drops, inhalations, parenteral and local application and as a carrier for oncological agents. The aim of the study based on the analysis of available literature was to explain the construction, metabolism and potential of HA application in the treatment of selected disease units, including orthopedic and oncological conditions.
PL
Kwas hialuronowy (HA) jest poliwęglowodanem, mukopolisacharydem (glikozoaminoglikanem), występującym naturalnie we wszystkich organizmach żywych. Ma identyczną budowę chemiczną zarówno u ssaków, jak i u bakterii. Łańcuch tego mukopolisacharydu może składać się nawet z kilku tysięcy podjednostek cukrowych. Unikalny wysokoelastyczny charakter HA, wraz z jego biozgodnością i brakiem potencjału immunogennego w stosunku do organizmu człowieka, przyczyniły się do zastosowania tej substancji w wielu rozwiązaniach klinicznych, w tym suplementacji płynu stawowego u pacjentów z zapaleniem stawów, jako środek pomocniczy w chirurgii okulistycznej i stomatologicznej oraz preparat przyspieszający gojenie ran pooperacyjnych. W ostatnich latach, w badaniach naukowych ocenia się właściwości HA jako potencjalnego nośnika leków w różnych drogach podania, w tym krople do oczu, do nosa, podane drogą wziewną, zastosowanie pozajelitowe i miejscowe oraz jako nośnika dla leków nowotworowych. Celem pracy, opartej na analizie dostępnej literatury, jest wyjaśnienie budowy, metabolizmu i możliwości wykorzystania HA w terapii wybranych jednostek chorobowych – w tym ortopedii i onkologii.
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