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1

Biochemical aspects of free radical mediated tissue injury

100%
Rybczynska M.
Postępy Higieny i Medycyny Doświadczalnej
|
1994
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vol. 48
|
issue 4
415-437
EN
A radical is any molecule that contains one or more unpaired electrons.Radicals are normally generated in many metabolic pathways.Some of these radicals can exist in free form and subsequentky interact with various tissue components resulting in dysfunction. The potential role oxygen- and xenobiotic- derived free radical in the pathology of several human diseases stimulated extensive research linking the toxity of numerous xenobiotics and disease processes to a free radical machanism.
2

A role of protein kinase C isoforms in tumorigenicity and apoptotic cells death

51%
Rybczynska M., Ksiazek K., Kaczmarek J.
Postępy Higieny i Medycyny Doświadczalnej
|
2000
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vol. 54
|
issue 6
777-796
EN
Protein kinase C comprises a family of at least 13 distinct serine/threonine kinase isoenzymes that have important action in transmembrane signal transduction pathways and have been reported to regulate cell proliferation, differentiation, cell-to-cell interaction, cytoskeletal functions, gene transcription, apoptosis and drug resistance. The results of investigations show differential redistribution isozymes in each organs and their specyfic activity in determined diseases.
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