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Acute hypersensitivity reaction following intravenous ferric carboxymaltose injection for iron deficiency anaemia: a case report

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Kumar N., Gautam P. B., Ahmad S., Qutub D., Prasad I.

Critical Care Innovations

2023

vol. 6

issue 1

41-45

Ferric carboxymaltose (FCM) is a non-dextran iron preparation used for intravenous treatment of iron deficiency anaemia (IDA) in adult patients with intolerance or poor response to oral iron therapy. Acute hypersensitivity reactions (HSRs) during iron infusions are very rare but can be life-threatening even after receiving a prior test dose. Here, we report a case of 42 years old female patient who underwent total laparoscopic hysterectomy with bilateral salpingo-oophorectomy. On the next postoperative day she received an injection of ferric carboxy maltose. She was diagnosed with IDA. She presented with the picture of an adverse drug reaction due to injection FCM. She was managed with oxygen, vasopressors, antihistaminics, intravenous fluids and, corticosteroids. She recovered well within 24 hours of intensive care unit admission following this adverse drug reaction. So, careful and precise observation is required in management of adverse reaction following ferric carboxymaltose and prompt recognition and treatment based on severity is warranted.

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1 Critical Care Innovations

1 2023

1 Ahmad S.

1 Gautam P. B.

1 Kumar N.

1 Prasad I.

1 Qutub D.

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Acute hypersensitivity reaction following intravenous ferric carboxymaltose injection for iron deficiency anaemia: a case report