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Primary cutaneous B-cell lymphoma located on the face and hard palate

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Brzeziński P., Chiriac A., Budurca R., Chiriac A. E., Pinteala T., Ivan L., Foia L.
OncoReview
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2014
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vol. 4
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issue 3
A113-116
EN
Introduction: Primary cutaneous B-cell lymphomas represent primary cutaneous lymphomas. The World Health Organization-European Organization for Research and Treatment of Cancer defines primary cutaneous B-cell limphomas as malignant lymphomas that are confined to the skin at presentation after complete staging procedures. Case report: We report a case of a woman with a cutaneous nodular B-cell lymphoma of the face, with very slow evolution that could easily be misdiagnosed. The patient had two non-ulcerated nodules on the left part of the face. A histological examination on both pieces following surgical excision showed a diffuse infiltrate of atypical B cells. The patient was subsequently directed to the Oncology Department for further investigation, but she died 24 hours afterwards due to one of the acute possible complications of the disease: pulmonary embolism. Conclusion: Cutaneous B-cell lymphoma is an unusual and rare skin neoplasm with a great range of clinical presentations and this is an alarm sign for apparent common skin lesion.
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Multiple primary malignant neoplasms - case report

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Amalinei C., Balan R., Ivan L., Socolov R., Socolov D., Cotutiu C.
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EN
The synchronous occurence of primary carcinomas of endometrium and ovary is well recognized. Malignant peripheral nerve sheath tumours (MPNSTs) may also rarely occur in patients diagnosed with malignancies of the female genital tract. We report a rare case of synchronous primary carcinomas of endometrium and ovary, followed by a metachronous retroperitoneal MPNST. Ascites cytology and endometrial biopsy, followed by hysterectomy and bilateral adnexectomy, were performed to remove the synchronous tumors. Histology was suggestive of synchronous endometrial endometrioid carcinoma and ovarian mucinous adenocarcinoma. After the removal of the retroperitoneal tumor, a MPNST was diagnosed by immunohistochemistry. The patient developed two consecutive vaginal tumors diagnosed as metastases of the previously diagnosed endometrial carcinoma. Although synchronous tumors of endometrium and ovary were relatively early staged and consequently had a favorable prognosis, subsequently occuring implants along the lower genital tract and the metachronous MPNST added up to a poor prognosis.
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