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Axi-symmetric deformation in the micropolar porous generalized thermoelastic medium

100%
Kumar R., Gupta R.
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2010
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issue 1
2
Content available remote

Crystal Field Theory of Magnetic Behaviour of Er_{2}(SO_{4})_{3}·8H_{2}O

81%
Gupta R., Ghosh U., Basu C.
Acta Physica Polonica A
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1996
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vol. 89
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issue 5-6
649-655
EN
Using the most rigorous approach of direct diagonalization of the Hamiltonian matrix constructed in the complete basis states (364 in number) of the Er^{3+} ion the observed magnetic susceptibility and anisotropy data of erbium sulphate octahydrate were simulated and the set of crystal field parameters was evaluated. This procedure automatically includes the effect of intermediate coupling and the J-mixing under the crystal field. It was also demonstrated that such rigorous calculation using complete basis states is necessary in order to evaluate the correct set of parameters which may widely differ from the values obtained from approximate calculations previously performed using partial number of basis states of the ion concerned.
3
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A DNA Biosensor Based Interface States of a Metal-Insulator-Semiconductor Diode for Biotechnology Applications

61%
Al-Ghamdi A., Al-Hartomy O., Gupta R., El-Tantawy F., Taskan E., Hasar H., Yakuphanoglu F.
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EN
We studied how a DNA sensor based on the interface states of a conventional metal-insulator-semiconductor diode can be prepared for biotechnology applications. For this purpose, the p-type silicon/metal diodes were prepared using SiO_2 and DNA layers. The obtained results were analyzed and compared with interfaces of DNA and SiO_2. It is seen that the ideality factor (1.82) of the Al/p-Si/SiO_2/DNA/Ag diode is lower than that (3.31) of the Al/p-Si/SiO_2/Ag diode. This indicates that the electronic performance of DNA/Si junction was better than that of SiO_2/Si junction. The interface states of the Al/p-Si/SiO_2/DNA/Ag and Al/p-Si/SiO_2/Ag junctions were analyzed by conductance technique. The obtained D_{it} values indicate that the DNA layer is an effective parameter to control the interface states of the conventional Si based on metal/semiconductor contacts. Results exhibited that DNA based metal-insulator-semiconductor diode could be used as DNA sensor for biotechnology applications.
4

Serodiagnostic efficacy of Mycobacterium tuberculosis 30/32-kDa mycolyl transferase complex, ESAT-6, and CFP-10 in patients with active tuberculosis

52%
Kumar G., Dagur P. K., Singh P. K., Shankar H., Yadav V. S., Katoch V. M., Bajaj B., Gupta R., Sengupta U., Joshi B.
Archivum Immunologiae et Therapiae Experimentalis
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2010
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vol. 58
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issue 1
57-65
EN
Elimination of tuberculosis (TB) largely depends upon definitive rapid diagnosis and treatment. Widely used diagnostic tests do not qualify for use in a developing country due to lack of either desired accuracy or their cost. In the present study an enzyme-linked immunosorbent assay was used to evaluate the diagnostic potential of an immuno-dominant 30/32-kDa mycolyl transferase complex (Ag85 complex) and Mycobacterium tuberculosis-specific proteins (ESAT-6 and CFP-10) of the RD1 region. Higher sensitivity (84.1%) with Ag85 complex was observed compared with ESAT-6 (64.9%) and CFP-10 (66%), with almost similar specificity (Ag85: 85.2%, ESAT-6: 88.9%, CFP-10: 85.2%), whereas the individual components of Ag85 complex, i.e. Ag85A, Ag85B, and Ag85C, showed sensitivities of 44.6, 34, and 80.9% and specificities of 55.6, 74.1, and 40.7% respectively. A cocktail of Ag85 complex, ESAT-6, CFP-10, Ag85A, Ag85B, and Ag85C antigens also could not help in increasing either sensitivity (51.1%) or specificity (85.2%). Furthermore, immunoblot analysis using clinical isolates as well as a standard strain (H37Rv) of M. tuberculosis also showed strong reactivity of sera from TB patients to Ag85 complex and, to a lesser extent, also to ESAT-6. To conclude, use of Ag85 complex along with ESAT-6 and CFP-10 seems to be promising in minimizing the heterogeneous sero-responses of adult TB cases.
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